Matches in DBpedia 2014 for { <http://dbpedia.org/resource/VAV1> ?p ?o. }
Showing items 1 to 21 of
21
with 100 items per page.
- VAV1 abstract "Proto-oncogene vav is a protein that in humans is encoded by the VAV1 gene.The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.".
- VAV1 entrezgene "7409".
- VAV1 wikiPageID "14284537".
- VAV1 wikiPageRevisionID "593275036".
- VAV1 hasPhotoCollection VAV1.
- VAV1 requireManualInspection "no".
- VAV1 summaryText "The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.".
- VAV1 updateCitations "yes".
- VAV1 updatePage "yes".
- VAV1 updateProteinBox "yes".
- VAV1 updateSummary "yes".
- VAV1 type Biomolecule.
- VAV1 type Protein.
- VAV1 type BiologicalObject.
- VAV1 comment "Proto-oncogene vav is a protein that in humans is encoded by the VAV1 gene.The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1.".
- VAV1 label "VAV1".
- VAV1 sameAs m.03c_8_v.
- VAV1 sameAs Q7906526.
- VAV1 sameAs Q7906526.
- VAV1 wasDerivedFrom VAV1?oldid=593275036.
- VAV1 isPrimaryTopicOf VAV1.