Matches in DBpedia 2014 for { <http://dbpedia.org/resource/VRK1> ?p ?o. }
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- VRK1 abstract "Serine/threonine-protein kinase VRK1 is an enzyme that in humans is encoded by the VRK1 gene.This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.".
- VRK1 entrezgene "7443".
- VRK1 wikiPageID "14819192".
- VRK1 wikiPageRevisionID "593290263".
- VRK1 hasPhotoCollection VRK1.
- VRK1 requireManualInspection "no".
- VRK1 summaryText "This gene encodes a member of the vaccinia-related kinase family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 and c-JUN.".
- VRK1 updateCitations "yes".
- VRK1 updatePage "yes".
- VRK1 updateProteinBox "yes".
- VRK1 updateSummary "yes".
- VRK1 type Biomolecule.
- VRK1 type Protein.
- VRK1 type BiologicalObject.
- VRK1 comment "Serine/threonine-protein kinase VRK1 is an enzyme that in humans is encoded by the VRK1 gene.This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas.".
- VRK1 label "VRK1".
- VRK1 sameAs m.03gz18y.
- VRK1 sameAs Q7907493.
- VRK1 sameAs Q7907493.
- VRK1 wasDerivedFrom VRK1?oldid=593290263.
- VRK1 isPrimaryTopicOf VRK1.