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- Vomitoxin abstract "Vomitoxin, also known as deoxynivalenol (DON), is a type B trichothecene, an epoxy-sesquiterpenoid. This mycotoxin occurs predominantly in grains such as wheat, barley, oats, rye, and maize, and less often in rice, sorghum, and triticale. The occurrence of deoxynivalenol is associated primarily with Fusarium graminearum (Gibberella zeae) and F. culmorum, both of which are important plant pathogens which cause fusarium head blight in wheat and gibberella or fusarium ear blight in maize. A direct relationship between the incidence of fusarium head blight and contamination of wheat with deoxynivalenol has been established. The incidence of fusarium head blight is strongly associated with moisture at the time of flowering (anthesis), and the timing of rainfall, rather than the amount, is the most critical factor. However, increased amount of moisture towards harvest time has been associated with lower amount of vomitoxin in wheat grain due to leaching of toxins. Furthermore, deoxynivalenol contents are significantly affected by the susceptibility of cultivars towards Fusarium species, previous crop, tillage practices, and fungicide use.F. graminearum grows optimally at a temperature of 25°C and at a water activity above 0.88. F. culmorum grows optimally at 21°C and at a water activity above 0.87. The geographical distribution of the two species appears to be related to temperature, F. graminearum being the more common species occurring in warmer climates. Deoxynivalenol has been implicated in incidents of mycotoxicoses in both humans and farm animals.When compared to other trichothecene mycotoxins which can form in grains and forages, vomitoxin is relatively mild. Reduced feed intake, with its accompanying decrease in performance, is the only symptom of vomitoxin toxicity livestock producers will likely encounter. This response to vomitoxin appears to occur through the central nervous system. Vomitoxin belongs to a class of mycotoxins (tricothecenes) which are strong inhibitors of protein synthesis; exposure to vomitoxin causes the brain to increase its uptake of the amino acid tryptophan and, in turn, its synthesis of serotonin. Increased levels of serotonin are believed to be responsible for the anorexic effects of DON and other tricothecenes. Irritation of the gastrointestinal tract may also play a role in reducing feed intake, and may also partially explain the high incidence of paraesophageal stomach ulcers observed in sows during feed refusal. Human foods: Vomitoxin is not a known carcinogen as with aflatoxin. Large amounts of grain with vomitoxin would have to be consumed to pose a health risk to humans. The U.S. Food and Drug Administration has established a level of 1 ppm (parts per million) restriction of vomitoxin. Companion animals: Dogs and cats are restricted to 5 ppm and of grains and grain byproducts and the grains are not to exceed 40% percent of the diet. Livestock and farm animals: In animals and livestock, vomitoxin causes a refusal to feed and lack of weight gain when fed above advised levels. Restrictions are set at 10 ppm for poultry and ruminating beef and feedlot cattle older than four months. Ingredients may not exceed 50% of the animal's diet. Dairy cow feed limits are set at 2 ppm.↑ ↑ ↑".
- Vomitoxin iupacName "(3α,​7α)-​3,​7,​15-​trihydroxy-​12,​13-​epoxytrichothec-​9-​en-​8-​one".
- Vomitoxin thumbnail Deoxynivalenol.png?width=300.
- Vomitoxin wikiPageExternalLink ajabssp.2011.231.241.
- Vomitoxin wikiPageExternalLink 556_EN.HTM.
- Vomitoxin wikiPageExternalLink Deoxynivalenol-MSDS.htm.
- Vomitoxin wikiPageExternalLink v47je05.htm.
- Vomitoxin wikiPageID "13038802".
- Vomitoxin wikiPageRevisionID "601598034".
- Vomitoxin c "15".
- Vomitoxin h "20".
- Vomitoxin hasPhotoCollection Vomitoxin.
- Vomitoxin imagefile "Deoxynivalenol.png".
- Vomitoxin iupacname "-​3,​7,​15-​trihydroxy-​12,​13-​epoxytrichothec-​9-​en-​8-​one".
- Vomitoxin o "6".
- Vomitoxin othernames "Deoxynivalenol".
- Vomitoxin othernames "Vomitoxin".
- Vomitoxin verifiedfields "changed".
- Vomitoxin verifiedrevid "470631708".
- Vomitoxin subject Category:Alcohols.
- Vomitoxin subject Category:Epoxides.
- Vomitoxin subject Category:Ketones.
- Vomitoxin subject Category:Mycotoxins.
- Vomitoxin subject Category:Spiro_compounds.
- Vomitoxin subject Category:Trichothecenes.
- Vomitoxin type Matter100020827.
- Vomitoxin type Mycotoxin115036536.
- Vomitoxin type Mycotoxins.
- Vomitoxin type PhysicalEntity100001930.
- Vomitoxin type PlantToxin115036638.
- Vomitoxin type Poison115032376.
- Vomitoxin type Substance100020090.
- Vomitoxin type Toxin115034074.
- Vomitoxin type ChemicalCompound.
- Vomitoxin type ChemicalSubstance.
- Vomitoxin type ChemicalSubstanceType.
- Vomitoxin type ChemicalObject.
- Vomitoxin type Thing.
- Vomitoxin comment "Vomitoxin, also known as deoxynivalenol (DON), is a type B trichothecene, an epoxy-sesquiterpenoid. This mycotoxin occurs predominantly in grains such as wheat, barley, oats, rye, and maize, and less often in rice, sorghum, and triticale. The occurrence of deoxynivalenol is associated primarily with Fusarium graminearum (Gibberella zeae) and F. culmorum, both of which are important plant pathogens which cause fusarium head blight in wheat and gibberella or fusarium ear blight in maize.".
- Vomitoxin label "Deossinivalenolo".
- Vomitoxin label "Deoxynivalenol".
- Vomitoxin label "Deoxynivalenol".
- Vomitoxin label "Déoxynivalénol".
- Vomitoxin label "Vomitoxin".
- Vomitoxin sameAs Deoxynivalenol.
- Vomitoxin sameAs Deoxynivalenol.
- Vomitoxin sameAs Déoxynivalénol.
- Vomitoxin sameAs Deossinivalenolo.
- Vomitoxin sameAs Deoxynivalenol.
- Vomitoxin sameAs m.02z48jh.
- Vomitoxin sameAs Q420518.
- Vomitoxin sameAs Q420518.
- Vomitoxin sameAs Vomitoxin.
- Vomitoxin wasDerivedFrom Vomitoxin?oldid=601598034.
- Vomitoxin depiction Deoxynivalenol.png.
- Vomitoxin isPrimaryTopicOf Vomitoxin.
