Matches in DBpedia 2014 for { <http://dbpedia.org/resource/WAY-100,135> ?p ?o. }
Showing items 1 to 43 of
43
with 100 items per page.
- WAY-100,135 abstract "WAY-100,135 is a serotonergic drug of the phenylpiperazine family which is used in scientific research. It acts as potent 5-HT1A receptor antagonist, and was originally believed to be highly selective, but further studies have demonstrated that it also acts as a partial agonist of the 5-HT1D receptor (pKi = 7.58; virtually the same affinity for 5-HT1A), and to a much lesser extent, of the 5-HT1B receptor (pKi = 5.82). These findings may have prompted the development of the related compound WAY-100,635, another purportedly selective and even more potent 5-HT1A antagonist, which was synthesized shortly thereafter. However, WAY-100,635 turned out to be non-selective as well, having been shown to act additionally as a potent D4 receptor agonist later on.".
- WAY-100,135 atcPrefix "None".
- WAY-100,135 casNumber "133025-23-7".
- WAY-100,135 iupacName "(S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide".
- WAY-100,135 pubchem "115111".
- WAY-100,135 thumbnail WAY-100,135_structure.png?width=300.
- WAY-100,135 wikiPageID "22617877".
- WAY-100,135 wikiPageRevisionID "593301327".
- WAY-100,135 atcPrefix "None".
- WAY-100,135 c "24".
- WAY-100,135 casNumber "133025".
- WAY-100,135 chembl "38288".
- WAY-100,135 chemspiderid "103008".
- WAY-100,135 h "33".
- WAY-100,135 hasPhotoCollection WAY-100,135.
- WAY-100,135 inchi "1".
- WAY-100,135 inchikey "UMTDAKAAYOXIKU-UHFFFAOYAA".
- WAY-100,135 iupacName "-N-tert-butyl-3--2-phenylpropanamide".
- WAY-100,135 iupharLigand "79".
- WAY-100,135 molecularWeight "395.536".
- WAY-100,135 n "3".
- WAY-100,135 o "2".
- WAY-100,135 pubchem "115111".
- WAY-100,135 smiles "c2ccccc2CCNCCN3c1ccccc1OC".
- WAY-100,135 stdinchi "1".
- WAY-100,135 stdinchikey "UMTDAKAAYOXIKU-UHFFFAOYSA-N".
- WAY-100,135 verifiedrevid "449588681".
- WAY-100,135 width "200".
- WAY-100,135 subject Category:5-HT1A_antagonists.
- WAY-100,135 subject Category:Amides.
- WAY-100,135 subject Category:Phenol_ethers.
- WAY-100,135 subject Category:Piperazines.
- WAY-100,135 type Drug.
- WAY-100,135 type DrugProduct.
- WAY-100,135 type FunctionalSubstance.
- WAY-100,135 comment "WAY-100,135 is a serotonergic drug of the phenylpiperazine family which is used in scientific research. It acts as potent 5-HT1A receptor antagonist, and was originally believed to be highly selective, but further studies have demonstrated that it also acts as a partial agonist of the 5-HT1D receptor (pKi = 7.58; virtually the same affinity for 5-HT1A), and to a much lesser extent, of the 5-HT1B receptor (pKi = 5.82).".
- WAY-100,135 label "WAY-100,135".
- WAY-100,135 sameAs m.05zxlj5.
- WAY-100,135 sameAs Q7946878.
- WAY-100,135 sameAs Q7946878.
- WAY-100,135 wasDerivedFrom WAY-100,135?oldid=593301327.
- WAY-100,135 depiction WAY-100,135_structure.png.
- WAY-100,135 isPrimaryTopicOf WAY-100,135.
