Matches in DBpedia 2014 for { <http://dbpedia.org/resource/ZIC3> ?p ?o. }
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- ZIC3 abstract "ZIC3 is a member of the Zinc finger of the cerebellum (ZIC) protein family.ZIC3 is classified as a ZIC protein due to conservation of the five C2H2 zinc fingers, which enables the protein to interact with DNA and proteins. Correct function of this protein family in critical for early development, and as such mutations of the genes encoding these proteins is known to result in various congenital defects. For example, mutation of ZIC3 is associated with heterotaxy, that is thought to occur due to the role of ZIC3 in initial left-right symmetry formation, which involves the maintaining redistributed Nodal after the asymmetry of the embryo is initially broken. Mutation of ZIC3 is also associated with various heart defects, such as heart looping, however these are thought to represent a mild form of heterotaxy. Mouse based studies have linked defective ZIC3 with neural tube defects (spina bifida) and skeletal defects.ZIC3 is also of particular interest as it has been shown to be required for maintenance of embryonic stem cell pluripotency.".
- ZIC3 entrezgene "7547".
- ZIC3 wikiPageID "14819225".
- ZIC3 wikiPageRevisionID "593550328".
- ZIC3 hasPhotoCollection ZIC3.
- ZIC3 requireManualInspection "no".
- ZIC3 updateCitations "yes".
- ZIC3 updatePage "yes".
- ZIC3 updateProteinBox "yes".
- ZIC3 updateSummary "yes".
- ZIC3 type Biomolecule.
- ZIC3 type Protein.
- ZIC3 type BiologicalObject.
- ZIC3 comment "ZIC3 is a member of the Zinc finger of the cerebellum (ZIC) protein family.ZIC3 is classified as a ZIC protein due to conservation of the five C2H2 zinc fingers, which enables the protein to interact with DNA and proteins. Correct function of this protein family in critical for early development, and as such mutations of the genes encoding these proteins is known to result in various congenital defects.".
- ZIC3 label "ZIC3".
- ZIC3 sameAs m.03gz1bn.
- ZIC3 sameAs Q3183845.
- ZIC3 sameAs Q3183845.
- ZIC3 sameAs ZIC3.
- ZIC3 wasDerivedFrom ZIC3?oldid=593550328.
- ZIC3 isPrimaryTopicOf ZIC3.