Matches in DBpedia 2014 for { <http://dbpedia.org/resource/ZP2> ?p ?o. }
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- ZP2 abstract "Zona pellucida sperm-binding protein 2 is a protein that in humans is encoded by the ZP2 gene.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.".
- ZP2 entrezgene "7783".
- ZP2 wikiPageID "14819252".
- ZP2 wikiPageRevisionID "593353091".
- ZP2 hasPhotoCollection ZP2.
- ZP2 requireManualInspection "no".
- ZP2 summaryText "The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.".
- ZP2 updateCitations "yes".
- ZP2 updatePage "yes".
- ZP2 updateProteinBox "yes".
- ZP2 updateSummary "yes".
- ZP2 type Biomolecule.
- ZP2 type Protein.
- ZP2 type BiologicalObject.
- ZP2 comment "Zona pellucida sperm-binding protein 2 is a protein that in humans is encoded by the ZP2 gene.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa.".
- ZP2 label "ZP2".
- ZP2 sameAs m.03gz1cp.
- ZP2 sameAs Q8063256.
- ZP2 sameAs Q8063256.
- ZP2 wasDerivedFrom ZP2?oldid=593353091.
- ZP2 isPrimaryTopicOf ZP2.