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- catalog abstract "The present volume contains the Proceedings of an EMBO Workshop organized in June 1983 by the institute of Virology, Veterinary Faculty, State University of Utrecht, The Netherlands. Some 70 scientists from 11 countries followed the invitation to present and discuss their recent data on the structure, replication, genetics and pathogenesis of coronaviruses. It was the second international meeting on these viruses; the Workshop, which was held in Zeist near Utrecht followed the example of the Wuerzburg symposium of October 1980. At that time it became clear that coronaviruses are unique in many respects. Once a group of viruses that were defined merely on the basis of their characteristic peplomer morphology, Coronaviridae family members are known today --to be constructed from essentially three polypeptides --to use a "nested set" of 5-6 subgenomic mRNAs in the expression of their large, positive and single stranded RNA genome, --to generate these subgenomic RNAs through specific fusion of noncontiguous sequences, --to mature by budding from intracellular membranes, --to cause persistent infection with neurological involvement and sometimes immunopathological conditions. These and many other findings have been established only very recently. The articles collected in this book reveal and/or further detail these findings. Since these Proceedings contain the combined scientific presentations of representatives from virtually all laboratories engaged in the field, they provide a fairly comprehensive review of the state of the art in coronavirology. The contents have been grouped into two main parts. The first part deals with the molecular biology of coronaviruses and contains contributions on viral proteins, virus maturation and on the structure and replication of viral RNAs. In the second part aspects of coronavirus pathogenesis are described including studies on genetic and immunological factors involved and on persistent infections in tissue culture. Both parts are preceded by synoptic papers complied by B.W.J. Mahy and V. ter Meulen respectively.".
- catalog contributor b1648580.
- catalog contributor b1648581.
- catalog created "c1984.".
- catalog date "1984".
- catalog date "c1984.".
- catalog dateCopyrighted "c1984.".
- catalog description "Includes bibliographical references and index.".
- catalog description "Once a group of viruses that were defined merely on the basis of their characteristic peplomer morphology, Coronaviridae family members are known today --to be constructed from essentially three polypeptides --to use a "nested set" of 5-6 subgenomic mRNAs in the expression of their large, positive and single stranded RNA genome, --to generate these subgenomic RNAs through specific fusion of noncontiguous sequences, --to mature by budding from intracellular membranes, --to cause persistent infection with neurological involvement and sometimes immunopathological conditions. These and many other findings have been established only very recently. The articles collected in this book reveal and/or further detail these findings. Since these Proceedings contain the combined scientific presentations of representatives from virtually all laboratories engaged in the field, they provide a fairly comprehensive review of the state of the art in coronavirology. ".
- catalog description "The contents have been grouped into two main parts. The first part deals with the molecular biology of coronaviruses and contains contributions on viral proteins, virus maturation and on the structure and replication of viral RNAs. In the second part aspects of coronavirus pathogenesis are described including studies on genetic and immunological factors involved and on persistent infections in tissue culture. Both parts are preceded by synoptic papers complied by B.W.J. Mahy and V. ter Meulen respectively.".
- catalog description "The present volume contains the Proceedings of an EMBO Workshop organized in June 1983 by the institute of Virology, Veterinary Faculty, State University of Utrecht, The Netherlands. Some 70 scientists from 11 countries followed the invitation to present and discuss their recent data on the structure, replication, genetics and pathogenesis of coronaviruses. It was the second international meeting on these viruses; the Workshop, which was held in Zeist near Utrecht followed the example of the Wuerzburg symposium of October 1980. At that time it became clear that coronaviruses are unique in many respects. ".
- catalog extent "xiii, 409 p. :".
- catalog hasFormat "Molecular biology and pathogenesis of coronaviruses.".
- catalog identifier "0306416166".
- catalog isFormatOf "Molecular biology and pathogenesis of coronaviruses.".
- catalog isPartOf "Advances in experimental medicine and biology ; v. 173".
- catalog issued "1984".
- catalog issued "c1984.".
- catalog language "eng".
- catalog publisher "New York : Plenum Press,".
- catalog relation "Molecular biology and pathogenesis of coronaviruses.".
- catalog subject "Coronaviridae Infections etiology Congresses.".
- catalog subject "Coronaviridae congresses".
- catalog subject "Coronavirus Infections etiology congresses".
- catalog subject "Coronavirus infections Pathogenesis Congresses.".
- catalog subject "Coronaviruses Congresses.".
- catalog subject "Molecular biology Congresses.".
- catalog subject "QR399 .E43 1983".
- catalog subject "QW 168.5.C8 E53m 1983".
- catalog subject "W1 AD559 v.173 1984".
- catalog title "Molecular biology and pathogenesis of coronaviruses / edited by P.J.M. Rottier ... [et al.].".
- catalog type "Conference proceedings. fast".
- catalog type "text".