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- catalog abstract "The International Symposium on Heparin, held May 13-15, 1974, in St. Louis, Missouri, as a part of the dedication of the Shoenberg Pavilion of the Jewish Hospital of St. Louis, was conceived as a forum to bring together physicians and scientists with a basic interest in the structure, function and clinical usefulness of heparin. Few naturally occurring substances have commanded the breadth of interest among members of the biomedical research community as this compound has. Aspects of its covalent and three-dimensional structure, its biosynthesis, its interaction with and effect on physiologically important moieties and its use as a therapeutic agent in a variety of disease states have been actively studied for the past several decades. Thus, the present state of these studies seemed to be a timely subject for discussion, not only to gather together in one place representative samples of the myriad of data on heparin but also to underscore the ever increasing necessity for communication between basic research and clinical practice.The content and organization of this monograph reflect the scope and importance of this substance. The first section deals with the molecular properties of heparin, including characterization of the basic structure, its biosynthetic origins, its determination and pharmacological standardization and the role of individual structural elements in its biological properties. The second section deals with the functional consequences of the interaction of heparin with various physiological entities including antithrombin III, platelets, and lipoprotein lipase. The last section deals with the several clinical uses of heparin, emphasizing not only the results of many trials but also the problems that remain to be elucidated.".
- catalog contributor b1977195.
- catalog contributor b1977196.
- catalog contributor b1977197.
- catalog contributor b1977198.
- catalog contributor b1977199.
- catalog contributor b1977200.
- catalog created "[1975]".
- catalog date "1975".
- catalog date "[1975]".
- catalog dateCopyrighted "[1975]".
- catalog description "Includes bibliographies and index.".
- catalog description "The International Symposium on Heparin, held May 13-15, 1974, in St. Louis, Missouri, as a part of the dedication of the Shoenberg Pavilion of the Jewish Hospital of St. Louis, was conceived as a forum to bring together physicians and scientists with a basic interest in the structure, function and clinical usefulness of heparin. Few naturally occurring substances have commanded the breadth of interest among members of the biomedical research community as this compound has. Aspects of its covalent and three-dimensional structure, its biosynthesis, its interaction with and effect on physiologically important moieties and its use as a therapeutic agent in a variety of disease states have been actively studied for the past several decades. Thus, the present state of these studies seemed to be a timely subject for discussion, not only to gather together in one place representative samples of the myriad of data on heparin but also to underscore the ever increasing necessity for communication between basic research and clinical practice.The content and organization of this monograph reflect the scope and importance of this substance. The first section deals with the molecular properties of heparin, including characterization of the basic structure, its biosynthetic origins, its determination and pharmacological standardization and the role of individual structural elements in its biological properties. The second section deals with the functional consequences of the interaction of heparin with various physiological entities including antithrombin III, platelets, and lipoprotein lipase. The last section deals with the several clinical uses of heparin, emphasizing not only the results of many trials but also the problems that remain to be elucidated.".
- catalog extent "x, 422 p. :".
- catalog hasFormat "Heparin.".
- catalog identifier "0306390523".
- catalog isFormatOf "Heparin.".
- catalog isPartOf "Advances in experimental medicine and biology ; v. 52".
- catalog issued "1975".
- catalog issued "[1975]".
- catalog language "eng".
- catalog publisher "New York : Plenum Press,".
- catalog relation "Heparin.".
- catalog subject "591.1/9/24".
- catalog subject "Heparin Congresses.".
- catalog subject "Heparin Therapeutic use Congresses.".
- catalog subject "Heparin congresses.".
- catalog subject "QP702.H4 I57 1974".
- catalog subject "QV 193 I61h 1974".
- catalog subject "W1 AD559 v.52 1975".
- catalog title "Heparin : structure, function, and clinical implications : [proceedings] / edited by Ralph A. Bradshaw and Stanford Wessler.".
- catalog type "Conference proceedings. fast".
- catalog type "text".