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catalog contributor b6873101.
catalog contributor b6873102.
catalog contributor b6873103.
catalog created "c1994.".
catalog date "1994".
catalog date "c1994.".
catalog dateCopyrighted "c1994.".
catalog description "1. Expression Systems for Retroviral Proteases / Jeffrey Stebbins and Christine Debouck -- 2. Genetic Approaches Designed to Minimize Cytotoxicity of Retroviral Protease / C.J. Rizzo and B.D. Korant -- 3. Host Strain Selection for Bacterial Expression of Toxic Proteins / Elizabeth Chen -- 4. Assay Methods for Retroviral Proteases / Christopher U.T. Hellen -- 5. Analysis of Human Immunodeficiency Virus Type 1 Protease Activity in Eukaryotic and Bacterial Cells / Andrew H. Kaplan, Marianne Manchester, Lorraine Everitt and Ronald Swanstrom -- 6. Synthetic Approaches to Continuous Assays of Retroviral Proteases / Grant A. Krafft and Gary T. Wang -- 7. Identification, Purification, and Cell Culture Assays of Retroviral Proteases / Klaus von der Helm, Sigrio Seelmeier, Alexei Kisselev and Hans Nitschko -- 8. Stability of Dimeric Retroviral Proteases / Paul L. Darke.".
catalog description "16. Rapid Determination of Endoprotease Specificity Using Peptide Mixtures and Edman Degradation Analysis / Frank R. Masiarz and Bruce A. Malcolm -- 17. Design of Tight-Binding Human Immunodeficiency Virus Type 1 Protease Inhibitors / Joseph P. Vacca -- 18. Design of Symmetry-Based, Peptidomimetic Inhibitors of Human Immunodeficiency Virus Protease / Dale J. Kempf -- 19. Advances in Automated Docking Applied to Human Immunodeficiency Virus Type 1 Protease / Michael D. Miller, Robert P. Sheridan, Simon K. Kearsley and Dennis J. Underwood -- 20. Use of Molecular Dynamics and Free Energy Perturbation Calculations in Anti-Human Immunodeficiency Virus Drug Design / Margaret A. McCarrick and Peter Kollman -- 21. Qualitative Study of Drug Resistance in Retroviral Protease Using Structural Modeling and Site-Directed Mutagenesis / J. Chris Culberson, Bruce L. Bush and Vinod V. Sardana.".
catalog description "9. Use of Steady State Kinetic Methods to Elucidate the Kinetic and Chemical Mechanisms of Retroviral Proteases / Thomas D. Meek, Evelyn J. Rodriguez and Thelma S. Angeles -- 10. X-Ray Structures of Retroviral Proteases and Their Inhibitor-Bound Complexes / Dagmar Ringe -- 11. Probing Structure-Function Relationships in Human Immunodeficiency Virus Type 1 Protease via Molecular Dynamics Simulation / William E. Harte, Jr. and David L. Beveridge -- 12. Relationships of Human Immunodeficiency Virus Protease with Eukaryotic Aspartic Proteases / Xin-Li Lin, Ying-Zhang Lin and Jordan Tang -- 13. Processing of Retroviral Gag Polyproteins: An in Vitro Approach / Carol Carter and Gabriele Zybarth -- 14. Subsite Preferences of Retroviral Proteinases / Ben M. Dunn, Alla Gustchina, Alexander Wlodawer and John Kay -- 15. Specificity of Retroviral Proteases: An Analysis of Viral and Nonviral Protein Substrates / Alfredo G. Tomasselli and Robert L. Heinrikson.".
catalog description "Includes bibliographical references and indexes.".
catalog extent "xxv, 432 p. :".
catalog identifier "0121821420 (alk. paper)".
catalog isPartOf "Methods in enzymology, 0076-6879 ; v. 241".
catalog issued "1994".
catalog issued "c1994.".
catalog language "eng".
catalog publisher "San Diego : Academic Press,".
catalog subject "547.758 20".
catalog subject "Aspartic Acid Endopeptidases.".
catalog subject "Enzymes Related to Viruses".
catalog subject "HIV (Viruses)".
catalog subject "HIV.".
catalog subject "Peptide Hydrolases.".
catalog subject "Proteolytic enzymes.".
catalog subject "QP601 .M49 v.241".
catalog subject "QU 136 R438 1994".
catalog subject "Retroviridae enzymology.".
catalog subject "Retroviridae.".
catalog subject "Retroviruses Enzymes.".
catalog subject "W1 ME9615K v.241 1994".
catalog tableOfContents "1. Expression Systems for Retroviral Proteases / Jeffrey Stebbins and Christine Debouck -- 2. Genetic Approaches Designed to Minimize Cytotoxicity of Retroviral Protease / C.J. Rizzo and B.D. Korant -- 3. Host Strain Selection for Bacterial Expression of Toxic Proteins / Elizabeth Chen -- 4. Assay Methods for Retroviral Proteases / Christopher U.T. Hellen -- 5. Analysis of Human Immunodeficiency Virus Type 1 Protease Activity in Eukaryotic and Bacterial Cells / Andrew H. Kaplan, Marianne Manchester, Lorraine Everitt and Ronald Swanstrom -- 6. Synthetic Approaches to Continuous Assays of Retroviral Proteases / Grant A. Krafft and Gary T. Wang -- 7. Identification, Purification, and Cell Culture Assays of Retroviral Proteases / Klaus von der Helm, Sigrio Seelmeier, Alexei Kisselev and Hans Nitschko -- 8. Stability of Dimeric Retroviral Proteases / Paul L. Darke.".
catalog tableOfContents "16. Rapid Determination of Endoprotease Specificity Using Peptide Mixtures and Edman Degradation Analysis / Frank R. Masiarz and Bruce A. Malcolm -- 17. Design of Tight-Binding Human Immunodeficiency Virus Type 1 Protease Inhibitors / Joseph P. Vacca -- 18. Design of Symmetry-Based, Peptidomimetic Inhibitors of Human Immunodeficiency Virus Protease / Dale J. Kempf -- 19. Advances in Automated Docking Applied to Human Immunodeficiency Virus Type 1 Protease / Michael D. Miller, Robert P. Sheridan, Simon K. Kearsley and Dennis J. Underwood -- 20. Use of Molecular Dynamics and Free Energy Perturbation Calculations in Anti-Human Immunodeficiency Virus Drug Design / Margaret A. McCarrick and Peter Kollman -- 21. Qualitative Study of Drug Resistance in Retroviral Protease Using Structural Modeling and Site-Directed Mutagenesis / J. Chris Culberson, Bruce L. Bush and Vinod V. Sardana.".
catalog tableOfContents "9. Use of Steady State Kinetic Methods to Elucidate the Kinetic and Chemical Mechanisms of Retroviral Proteases / Thomas D. Meek, Evelyn J. Rodriguez and Thelma S. Angeles -- 10. X-Ray Structures of Retroviral Proteases and Their Inhibitor-Bound Complexes / Dagmar Ringe -- 11. Probing Structure-Function Relationships in Human Immunodeficiency Virus Type 1 Protease via Molecular Dynamics Simulation / William E. Harte, Jr. and David L. Beveridge -- 12. Relationships of Human Immunodeficiency Virus Protease with Eukaryotic Aspartic Proteases / Xin-Li Lin, Ying-Zhang Lin and Jordan Tang -- 13. Processing of Retroviral Gag Polyproteins: An in Vitro Approach / Carol Carter and Gabriele Zybarth -- 14. Subsite Preferences of Retroviral Proteinases / Ben M. Dunn, Alla Gustchina, Alexander Wlodawer and John Kay -- 15. Specificity of Retroviral Proteases: An Analysis of Viral and Nonviral Protein Substrates / Alfredo G. Tomasselli and Robert L. Heinrikson.".
catalog title "Retroviral proteases / edited by Lawrence C. Kuo, Jules A. Shafer.".
catalog type "text".