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• catalog contributor b7814449.
• catalog created "c1994.".
• catalog date "1994".
• catalog date "c1994.".
• catalog dateCopyrighted "c1994.".
• catalog description "Can the kinetic rule be circumbented -- Physiological modeling of gene expression -- Modeling the consequences of gene expression -- Mechanistic models of bacterial metabolism -- Sterol-dependent regulation of HMG-CoA reductase gene expression -- Control of cholesterol synthesis and elimination -- Oxysterol effects on HMG CoA reductase -- Results of computer-based simulations -- Dioxin metabolism, gene expression, and risk assessment.".
• catalog description "Includes bibliographical references and index.".
• catalog description "Quantifying gene expression -- Timing of gene expression in bacteria -- Timing of adaptive gene expression in mammals -- Physical basis for the time course of gene expression -- Simplifying concept of fractional change -- Variety in the time ourse of maximal enzyme induction -- Modeling gene expression with simulation software -- Using the idea of approximation -- Example of the traditional approach -- Solving a model of gene expression with a simulation program -- Simulation programs make mathematics accessible to biologists -- Kinetic modeling of gene expression.".
• catalog description "Role of computer simulation in molecular biology -- Model of gene expression based on compartmental analysis -- Kinetic behavior of a single compartment -- Assumptions and nomenclature used in modeling systems -- Transfer rates between compartments are related to half-lives -- Compartmental models are self-assembling and predict steady state relationships -- Relationship between simulation and experimentation -- Resources for computer simulation -- Time and quantity in gene expression -- Timing of gene expression -- Flow of genetic information.".
• catalog description "Towards a comprehensive model of gene expression -- Creating a computer program to simulate gene expression -- Translational control -- Obtaining data for simulation experiments -- Modeling transcriptional controls -- Lags and the idea of relaxation time -- Law of diminishing returns -- Interrelationship of messenger RNA and protein metabolism -- Necessary balance of synthesis and degradation -- Transcriptional controls are most efficient -- Rapidly inducible proteins are encoded by labile mRNAs -- Do exons coordinate mRNA and protein stability.".
• catalog extent "92 p. :".
• catalog identifier "1570592012".
• catalog isPartOf "Molecular biology intelligence unit (Unnumbered)".
• catalog isPartOf "Molecular biology intelligence unit".
• catalog issued "1994".
• catalog issued "c1994.".
• catalog language "eng".
• catalog publisher "Austin, Tex. : R.G. Landes Co.,".
• catalog subject "574.87/322/0113416 20".
• catalog subject "Computer Simulation.".
• catalog subject "Gene Expression.".
• catalog subject "Gene expression Computer simulation.".
• catalog subject "Models, Genetic.".
• catalog subject "QH450 .H37 1994".
• catalog tableOfContents "Can the kinetic rule be circumbented -- Physiological modeling of gene expression -- Modeling the consequences of gene expression -- Mechanistic models of bacterial metabolism -- Sterol-dependent regulation of HMG-CoA reductase gene expression -- Control of cholesterol synthesis and elimination -- Oxysterol effects on HMG CoA reductase -- Results of computer-based simulations -- Dioxin metabolism, gene expression, and risk assessment.".
• catalog tableOfContents "Quantifying gene expression -- Timing of gene expression in bacteria -- Timing of adaptive gene expression in mammals -- Physical basis for the time course of gene expression -- Simplifying concept of fractional change -- Variety in the time ourse of maximal enzyme induction -- Modeling gene expression with simulation software -- Using the idea of approximation -- Example of the traditional approach -- Solving a model of gene expression with a simulation program -- Simulation programs make mathematics accessible to biologists -- Kinetic modeling of gene expression.".
• catalog tableOfContents "Role of computer simulation in molecular biology -- Model of gene expression based on compartmental analysis -- Kinetic behavior of a single compartment -- Assumptions and nomenclature used in modeling systems -- Transfer rates between compartments are related to half-lives -- Compartmental models are self-assembling and predict steady state relationships -- Relationship between simulation and experimentation -- Resources for computer simulation -- Time and quantity in gene expression -- Timing of gene expression -- Flow of genetic information.".
• catalog tableOfContents "Towards a comprehensive model of gene expression -- Creating a computer program to simulate gene expression -- Translational control -- Obtaining data for simulation experiments -- Modeling transcriptional controls -- Lags and the idea of relaxation time -- Law of diminishing returns -- Interrelationship of messenger RNA and protein metabolism -- Necessary balance of synthesis and degradation -- Transcriptional controls are most efficient -- Rapidly inducible proteins are encoded by labile mRNAs -- Do exons coordinate mRNA and protein stability.".
• catalog title "Kinetic modeling of gene expression / James L. Hargrove.".
• catalog type "text".