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• catalog abstract "Remarkable progress has occurred over the past 30 years in the study of zinc metabolism in humans, as researchers continue to investigate zinc's important nutritional and immunological roles in the body. Zinc deficiency has been linked to numerous immune deficiency disorders and to growth retardation in children and adolescents. In addition, zinc has proven to be an effective therapy for Wilson's disease and the once fatal acrodermatitis enteropathica. Biochemistry of Zinc critically examines these and other significant advances in basic research and relates them to the biological results of insufficient amounts of zinc in the body. This comprehensive text describes several recently discovered effects of zinc deficiency - such as anergy, and decreased levels of IL-2 and IL-1 production, natural killer cell activity, and active thymulin peptide - and assesses their clinical implications in the treatment of zinc-related immune disorders. It covers all the vital biochemical information on zinc and its functions, including its interactions with enzymes, hormones, lipid metabolism, cells, neurobiology, and other micronutrients. The book also discusses the relevant historical aspects of zinc and features an informative chapter on techniques for measuring zinc in biological samples, using atomic absorption spectrophotometry. Providing a solid foundation for future research, Biochemistry of Zinc is a thorough, state-of-the-art resource for researchers and students in biochemistry, nutrition, and medical research, as well as physicians who are likely to encounter zinc-related problems in their practice.".
• catalog contributor b7961922.
• catalog created "c1993.".
• catalog date "1993".
• catalog date "c1993.".
• catalog dateCopyrighted "c1993.".
• catalog description "(cont) Moderate deficiency of zinc -- Zinc deficiency in sickle-cell disease -- Mild deficiency of zinc -- Miscellaneous clinical conditions -- Interactions of zinc with other micronutrients -- Interactions of zinc and iron in humans -- Zinc and copper -- Manganese and zinc -- Cadmium, lead and zinc -- Calcium and zinc -- Magnesium and zinc -- Sodium and zinc -- Vitamin A and zinc -- Vitamin B₆ and zinc -- Vitamin D and zinc -- Vitamin E and zinc -- Folic acid and zinc -- Biotin and zinc -- Techniques for measurement of zinc in biological samples -- Determination of zinc in plasma -- Zinc in platelets, lymphocytes and granulocytes by flameless atomic absorption spectrophotometry.".
• catalog description "(cont) Zinc and brain hormones -- Zinc and lipid metabolism -- Essential fatty acids -- Cholesterol -- Phospholipids -- Triglycerides -- Lipoproteins -- Lipid peroxidation -- Zinc and cells -- Lymphocytes -- Mast cells -- Platelets -- Macrophages and polymorphonuclear granulocytes -- Ecto 5'-nucleotidase -- Zinc and free radicals -- Zinc and erythrocytes -- Transport of zinc across the erythrocyte membrane -- Sickle-cell membranes and Zn² -- Zinc and neurobiology -- Zinc and cell division -- Zinc and tubulin -- Zinc and brain function -- Zinc homeostasis -- Zinc-related enzymes in the brain -- Zinc and the hippocampus -- Zinc and human brain -- Zinc and epilepsy -- Zinc and immunity -- Studies in animal models -- Zinc deficiency and immune functions in humans -- Metabolism in zinc -- Dietary sources of zinc -- Absorption -- Intake and excretion of zinc -- Excretion of zinc -- Requirements for zinc -- Peripheral utilization -- Blood transport: zinc in plasma and red cells -- Homeostasis of zinc -- Clinical spectrum of human zinc deficiency -- Severe manifestations of zinc deficiency.".
• catalog description "Biochemistry of Zinc critically examines these and other significant advances in basic research and relates them to the biological results of insufficient amounts of zinc in the body. This comprehensive text describes several recently discovered effects of zinc deficiency - such as anergy, and decreased levels of IL-2 and IL-1 production, natural killer cell activity, and active thymulin peptide - and assesses their clinical implications in the treatment of zinc-related immune disorders. It covers all the vital biochemical information on zinc and its functions, including its interactions with enzymes, hormones, lipid metabolism, cells, neurobiology, and other micronutrients. The book also discusses the relevant historical aspects of zinc and features an informative chapter on techniques for measuring zinc in biological samples, using atomic absorption spectrophotometry.".
• catalog description "Historical aspects of zinc -- Zinc deficiency in microorganisms, plants and animals -- Zinc deficiency in humans -- Zinc and enzymes -- Functions of zinc in metalloenzymes -- Binding sites of zinc in enzymes -- DNA and RNA polymerases -- Role of zinc in protection of essential thiol enzymes -- Cytochrome c oxidase -- Enzyme changes in zinc deficiency -- Enzymes involved in nucleic acids -- Alkaline phosphatase -- Zinc and gene expression -- Zinc fingers: a novel protein motif for gene expression -- Repetitive Zn-binding domains in TFIIIA -- Zinc: a necessary cofactor for domain binding to DNA -- GAL genes of Saccharomyces cerevisiae -- Hormone receptors -- Biochemistry of metallothionein -- Classification -- Primary structure -- Metal-binding sites -- Spatial structure -- Inducibility of metallothionein -- Molecular mechanisms of metallothionein induction -- Functional aspects -- Zinc and hormones -- Zinc and growth -- Zinc and reproductive functions -- Zinc and glucose metabolism -- Zinc and adrenals -- Zinc and prolactin -- Zinc and thyroid and parathyroid hormones.".
• catalog description "Includes bibliographical references and index.".
• catalog description "Providing a solid foundation for future research, Biochemistry of Zinc is a thorough, state-of-the-art resource for researchers and students in biochemistry, nutrition, and medical research, as well as physicians who are likely to encounter zinc-related problems in their practice.".
• catalog description "Remarkable progress has occurred over the past 30 years in the study of zinc metabolism in humans, as researchers continue to investigate zinc's important nutritional and immunological roles in the body. Zinc deficiency has been linked to numerous immune deficiency disorders and to growth retardation in children and adolescents. In addition, zinc has proven to be an effective therapy for Wilson's disease and the once fatal acrodermatitis enteropathica.".
• catalog extent "xiii, 303 p. :".
• catalog hasFormat "Biochemistry of zinc.".
• catalog identifier "0306443996".
• catalog isFormatOf "Biochemistry of zinc.".
• catalog isPartOf "Biochemistry of the elements ; v. 11".
• catalog isPartOf "[The language of science]".
• catalog issued "1993".
• catalog issued "c1993.".
• catalog language "eng".
• catalog publisher "New York : Plenum Press,".
• catalog relation "Biochemistry of zinc.".
• catalog subject "612/.01524 20".
• catalog subject "QP535.Z6 P69 1993".
• catalog subject "QU 130 B6144 1980 v. 11".
• catalog subject "Zinc Metabolism.".
• catalog subject "Zinc Physiological effect.".
• catalog subject "Zinc deficiency.".
• catalog subject "Zinc metabolism.".
• catalog tableOfContents "(cont) Moderate deficiency of zinc -- Zinc deficiency in sickle-cell disease -- Mild deficiency of zinc -- Miscellaneous clinical conditions -- Interactions of zinc with other micronutrients -- Interactions of zinc and iron in humans -- Zinc and copper -- Manganese and zinc -- Cadmium, lead and zinc -- Calcium and zinc -- Magnesium and zinc -- Sodium and zinc -- Vitamin A and zinc -- Vitamin B₆ and zinc -- Vitamin D and zinc -- Vitamin E and zinc -- Folic acid and zinc -- Biotin and zinc -- Techniques for measurement of zinc in biological samples -- Determination of zinc in plasma -- Zinc in platelets, lymphocytes and granulocytes by flameless atomic absorption spectrophotometry.".
• catalog tableOfContents "(cont) Zinc and brain hormones -- Zinc and lipid metabolism -- Essential fatty acids -- Cholesterol -- Phospholipids -- Triglycerides -- Lipoproteins -- Lipid peroxidation -- Zinc and cells -- Lymphocytes -- Mast cells -- Platelets -- Macrophages and polymorphonuclear granulocytes -- Ecto 5'-nucleotidase -- Zinc and free radicals -- Zinc and erythrocytes -- Transport of zinc across the erythrocyte membrane -- Sickle-cell membranes and Zn² -- Zinc and neurobiology -- Zinc and cell division -- Zinc and tubulin -- Zinc and brain function -- Zinc homeostasis -- Zinc-related enzymes in the brain -- Zinc and the hippocampus -- Zinc and human brain -- Zinc and epilepsy -- Zinc and immunity -- Studies in animal models -- Zinc deficiency and immune functions in humans -- Metabolism in zinc -- Dietary sources of zinc -- Absorption -- Intake and excretion of zinc -- Excretion of zinc -- Requirements for zinc -- Peripheral utilization -- Blood transport: zinc in plasma and red cells -- Homeostasis of zinc -- Clinical spectrum of human zinc deficiency -- Severe manifestations of zinc deficiency.".
• catalog tableOfContents "Historical aspects of zinc -- Zinc deficiency in microorganisms, plants and animals -- Zinc deficiency in humans -- Zinc and enzymes -- Functions of zinc in metalloenzymes -- Binding sites of zinc in enzymes -- DNA and RNA polymerases -- Role of zinc in protection of essential thiol enzymes -- Cytochrome c oxidase -- Enzyme changes in zinc deficiency -- Enzymes involved in nucleic acids -- Alkaline phosphatase -- Zinc and gene expression -- Zinc fingers: a novel protein motif for gene expression -- Repetitive Zn-binding domains in TFIIIA -- Zinc: a necessary cofactor for domain binding to DNA -- GAL genes of Saccharomyces cerevisiae -- Hormone receptors -- Biochemistry of metallothionein -- Classification -- Primary structure -- Metal-binding sites -- Spatial structure -- Inducibility of metallothionein -- Molecular mechanisms of metallothionein induction -- Functional aspects -- Zinc and hormones -- Zinc and growth -- Zinc and reproductive functions -- Zinc and glucose metabolism -- Zinc and adrenals -- Zinc and prolactin -- Zinc and thyroid and parathyroid hormones.".
• catalog title "Biochemistry of zinc / Ananda S. Prasad.".
• catalog type "text".