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- catalog abstract ""The Causes and Consequences of Chromosomal Aberrations explores one of the most dramatic examples of genomic instability-chromosomal aberrations. It describes some of the more recent techniques used to map genes within the human genome, study chromosomal aberrations at the cellular level, and define the organization of the interphase nucleus. General overviews are provided to build a conceptual framework for understanding the generality and specificity of chromosomal aberrations. The Causes and Consequences of Chromosomal Aberrations also explores the role of recombinases and topoisomerases in the development of chromosomal aberrations. It contains studies of chromosomal aberrations, which offer separate instructive treatises on specific malignancies. The Causes and Consequences of Chromosomal Aberrations is useful to medical and graduate students, physicians, molecular biologists, and cytogeneticists. It will benefit anyone interested in the concepts, contributions, and development in the field of molecular cytogenetics."--Publisher description (LoC).".
- catalog contributor b7977727.
- catalog created "c1993.".
- catalog date "1993".
- catalog date "c1993.".
- catalog dateCopyrighted "c1993.".
- catalog description ""The Causes and Consequences of Chromosomal Aberrations explores one of the most dramatic examples of genomic instability-chromosomal aberrations. It describes some of the more recent techniques used to map genes within the human genome, study chromosomal aberrations at the cellular level, and define the organization of the interphase nucleus. General overviews are provided to build a conceptual framework for understanding the generality and specificity of chromosomal aberrations. The Causes and Consequences of Chromosomal Aberrations also explores the role of recombinases and topoisomerases in the development of chromosomal aberrations. It contains studies of chromosomal aberrations, which offer separate instructive treatises on specific malignancies. The Causes and Consequences of Chromosomal Aberrations is useful to medical and graduate students, physicians, molecular biologists, and cytogeneticists. It will benefit anyone interested in the concepts, contributions, and development in the field of molecular cytogenetics."--Publisher description (LoC).".
- catalog description "(cont) Cytogenetics of acquired chromosomal abnormalities: from chromosome to gene / Roland Berger -- Road to the Ig/myc translocation / George Klein -- From chromosomes to oncogenes: a personal perspective / Peter C. Nowell.".
- catalog description "(cont) Role of site-directed recombinases in physiologic and pathologic chromosomal rearrangements / Michael R. Lieber -- Mechanisms of formation of chromosomal aberrations: role of eukaryotic DNA topoisomerases / Yves Pommier and Richard Bertrand -- Chromosomal translocations involving the c-myc oncogene in lymphoid neoplasia / Riccardo Dalla-Favera -- Human B-cell neoplasms with the t(11;14) (q13;q32) and t(14;18) (q32;q21) chromosome translocations / Yoshihide Tsujimoto -- Themes and variations among the mature lymphoid leukemias / M.J.S. Dyer and D. Catovsky -- Ph-positive leukemia / Nora Heisterkamp [and others] -- Causes and consequences of chromosomal aberrations: acute myeloid leukemia / Maria R. Baer and Clara D. Bloomfield -- Structural and functional consequences of chromosomal translocation in human T-cell tumors / T.H. Rabbitts and T. Boehm -- Lymphoid malignancies that disrupt homeotic and "HLH" genes / Peter D. Aplan and Ilan R. Kirsch -- Misadventures of RB1 / Brenda L. Gallie -- Cytogenetic characterization of colorectal and breast carcinomas / B. Dutrilaux [and others].".
- catalog description "Includes bibliographical references and index.".
- catalog description "Molecular cytogenetics: applications of fluorescence hybridization to chromosomal aberrations and cancer genetics / Yigong Xing and Jeanne Bentley Lawrence -- Gene mapping by genetic linkage and somatic cell hybrid analysis / O. Wesley McBride -- Chromosome aberrations in simpler eukaryotes / Andres Aguilera and Hannah L. Klein -- myc-associated chromosomal translocations and rearrangements in plasmacytomagenesis in mice / Francis Wiener and Michael Potter -- Acquired chromosomal aberrations in normal individuals / Alain Aurias -- Chromosome changes in leukemia and cancer and their molecular limning / Avery A. Sandberg -- Clonal T-cell proliferations in ataxia telangiectasia / Marc-Henri Stern -- Hybrid antigen receptor genes: a model of translocation in lymphoid cells and a marker for the risk of developing a lymphoid malignancy / Stanley Lipkowitz and Ilan R. Kirsch -- Constitutional chromosome aneuploidy and cancer / Nicoletta Sacchi -- Deletions of 5q and myeloid leukemias / Carol A. Westbrook and Michelle M. Le Beau.".
- catalog extent "ix, 534 p. :".
- catalog identifier "0849388937".
- catalog issued "1993".
- catalog issued "c1993.".
- catalog language "eng".
- catalog publisher "Boca Raton : CRC Press,".
- catalog subject "616/.042 20".
- catalog subject "Chromosome Aberrations genetics.".
- catalog subject "Chromosome Disorders genetics.".
- catalog subject "Chromosome abnormalities.".
- catalog subject "Cytogenetics.".
- catalog subject "Molecular genetics.".
- catalog subject "QS 677 C374".
- catalog subject "RB155.5 .C38 1993".
- catalog tableOfContents "(cont) Cytogenetics of acquired chromosomal abnormalities: from chromosome to gene / Roland Berger -- Road to the Ig/myc translocation / George Klein -- From chromosomes to oncogenes: a personal perspective / Peter C. Nowell.".
- catalog tableOfContents "(cont) Role of site-directed recombinases in physiologic and pathologic chromosomal rearrangements / Michael R. Lieber -- Mechanisms of formation of chromosomal aberrations: role of eukaryotic DNA topoisomerases / Yves Pommier and Richard Bertrand -- Chromosomal translocations involving the c-myc oncogene in lymphoid neoplasia / Riccardo Dalla-Favera -- Human B-cell neoplasms with the t(11;14) (q13;q32) and t(14;18) (q32;q21) chromosome translocations / Yoshihide Tsujimoto -- Themes and variations among the mature lymphoid leukemias / M.J.S. Dyer and D. Catovsky -- Ph-positive leukemia / Nora Heisterkamp [and others] -- Causes and consequences of chromosomal aberrations: acute myeloid leukemia / Maria R. Baer and Clara D. Bloomfield -- Structural and functional consequences of chromosomal translocation in human T-cell tumors / T.H. Rabbitts and T. Boehm -- Lymphoid malignancies that disrupt homeotic and "HLH" genes / Peter D. Aplan and Ilan R. Kirsch -- Misadventures of RB1 / Brenda L. Gallie -- Cytogenetic characterization of colorectal and breast carcinomas / B. Dutrilaux [and others].".
- catalog tableOfContents "Molecular cytogenetics: applications of fluorescence hybridization to chromosomal aberrations and cancer genetics / Yigong Xing and Jeanne Bentley Lawrence -- Gene mapping by genetic linkage and somatic cell hybrid analysis / O. Wesley McBride -- Chromosome aberrations in simpler eukaryotes / Andres Aguilera and Hannah L. Klein -- myc-associated chromosomal translocations and rearrangements in plasmacytomagenesis in mice / Francis Wiener and Michael Potter -- Acquired chromosomal aberrations in normal individuals / Alain Aurias -- Chromosome changes in leukemia and cancer and their molecular limning / Avery A. Sandberg -- Clonal T-cell proliferations in ataxia telangiectasia / Marc-Henri Stern -- Hybrid antigen receptor genes: a model of translocation in lymphoid cells and a marker for the risk of developing a lymphoid malignancy / Stanley Lipkowitz and Ilan R. Kirsch -- Constitutional chromosome aneuploidy and cancer / Nicoletta Sacchi -- Deletions of 5q and myeloid leukemias / Carol A. Westbrook and Michelle M. Le Beau.".
- catalog title "The Causes and consequences of chromosomal aberrations / edited by Ilan R. Kirsch.".
- catalog type "text".