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• catalog abstract "September 1994. "The most impassioned and publicly visible of all genetic races" (The New York Times) comes to a triumphant close with the discovery of BRCA1, popularly known as the breast cancer gene. The result of a four-year international effort involving scientists from the United States, Canada, England, France, and Japan, among others, it is hailed as one of the most significant discoveries in recent medical science. Breakthrough is the brilliant account of this historic undertaking, its origins and development, and its implications for the future. With vivid profiles of the people and politics behind the events, Kevin Davies and Michael White unfold a scientific detective story that offers a rare glimpse into the complex - and fiercely competitive - world of genetic research. The race began in October 1990, when Dr. Mary-Claire King startled the American society of Human Genetics with the news that after fifteen years, her research group had found irrefutable evidence of a gene linking heredity and the risk of breast cancer. From that moment on, the quest to isolate the gene became the focus of worldwide attention, eventually reaching fever pitch. In a race against time and one another, "researchers relentlessly zeroed in on a piece of DNA too small to see, for a prize too enormous to contemplate." In addition to the pioneering Dr. King, the distinguished scientists profiled include the renowned Francis Collins, who discovered the genes for cystic fibrosis and Huntington's disease, and Mark Skolnick, the entrepreneurial founder of Myriad Genetics, who made fascinating use of the genealogical records of Mormons in his quest for the gene. The intensity of the project brought out the extremes of scientific research, from exhilarating enthusiasm and cooperation to heated rivalry. Beyond its fast-paced chronicle of discovery, Breakthrough is also a story of the politics of illness, focusing on the impact of the women's movement on breast cancer research and the changing attitudes of the past twenty-five years. Although, as the authors state, our "heightened awareness of the disease has been very late in coming," there is genuine cause for hope. Looking to the future, they explore current methods of screening and treatment as well as the prospects for a cure.".
• catalog alternative "Race to find the breast cancer gene".
• catalog contributor b8982346.
• catalog contributor b8982347.
• catalog created "c1996.".
• catalog date "1996".
• catalog date "c1996.".
• catalog dateCopyrighted "c1996.".
• catalog description "1. King Takes Night: The Opening Shot in the Battle against Breast Cancer -- 2. The Mystery of One in Nine: What Causes Breast Cancer? -- 3. Genetic Detective: The Mary-Claire King Story -- 4. The Long Haul: The Early Years of Breast Cancer Genetics -- 5. The Collins Crusade: Blazing the Trail for Genetic Research -- 6. Zeroing in, Chilling out: Fierce Competitors Join the Race -- 7. The Screening Era Begins: Debating the Ethics of Genetics -- 8. Myriad Possibilities: Mark Skolnick Turns Genealogy into Genes -- 9. Breakthrough!: The Race Is Over, the Gene Is Found -- 10. The End of the Epidemic?: What the Gene Promises and What Remains to Be Done -- Appendix: What Women Should Know about Current Treatments.".
• catalog description "In addition to the pioneering Dr. King, the distinguished scientists profiled include the renowned Francis Collins, who discovered the genes for cystic fibrosis and Huntington's disease, and Mark Skolnick, the entrepreneurial founder of Myriad Genetics, who made fascinating use of the genealogical records of Mormons in his quest for the gene. The intensity of the project brought out the extremes of scientific research, from exhilarating enthusiasm and cooperation to heated rivalry. Beyond its fast-paced chronicle of discovery, Breakthrough is also a story of the politics of illness, focusing on the impact of the women's movement on breast cancer research and the changing attitudes of the past twenty-five years. Although, as the authors state, our "heightened awareness of the disease has been very late in coming," there is genuine cause for hope. Looking to the future, they explore current methods of screening and treatment as well as the prospects for a cure.".
• catalog description "Includes bibliographical references (p.285-302) and index.".
• catalog description "September 1994. "The most impassioned and publicly visible of all genetic races" (The New York Times) comes to a triumphant close with the discovery of BRCA1, popularly known as the breast cancer gene. The result of a four-year international effort involving scientists from the United States, Canada, England, France, and Japan, among others, it is hailed as one of the most significant discoveries in recent medical science. Breakthrough is the brilliant account of this historic undertaking, its origins and development, and its implications for the future. With vivid profiles of the people and politics behind the events, Kevin Davies and Michael White unfold a scientific detective story that offers a rare glimpse into the complex - and fiercely competitive - world of genetic research.".
• catalog description "The race began in October 1990, when Dr. Mary-Claire King startled the American society of Human Genetics with the news that after fifteen years, her research group had found irrefutable evidence of a gene linking heredity and the risk of breast cancer. From that moment on, the quest to isolate the gene became the focus of worldwide attention, eventually reaching fever pitch. In a race against time and one another, "researchers relentlessly zeroed in on a piece of DNA too small to see, for a prize too enormous to contemplate."".
• catalog extent "ix, 310 p. ;".
• catalog hasFormat "Breakthrough.".
• catalog identifier "0471120251 (cloth : alk. paper)".
• catalog isFormatOf "Breakthrough.".
• catalog issued "1996".
• catalog issued "c1996.".
• catalog language "eng".
• catalog publisher "New York : J. Wiley,".
• catalog relation "Breakthrough.".
• catalog subject "616.99/449071 20".
• catalog subject "Breast Cancer Genetic aspects.".
• catalog subject "Breast Neoplasms etiology.".
• catalog subject "Breast Neoplasms genetics.".
• catalog subject "Genetic Linkage".
• catalog subject "RC280.B8 D3626 1996".
• catalog subject "WP 870 D249b 1996".
• catalog tableOfContents "1. King Takes Night: The Opening Shot in the Battle against Breast Cancer -- 2. The Mystery of One in Nine: What Causes Breast Cancer? -- 3. Genetic Detective: The Mary-Claire King Story -- 4. The Long Haul: The Early Years of Breast Cancer Genetics -- 5. The Collins Crusade: Blazing the Trail for Genetic Research -- 6. Zeroing in, Chilling out: Fierce Competitors Join the Race -- 7. The Screening Era Begins: Debating the Ethics of Genetics -- 8. Myriad Possibilities: Mark Skolnick Turns Genealogy into Genes -- 9. Breakthrough!: The Race Is Over, the Gene Is Found -- 10. The End of the Epidemic?: What the Gene Promises and What Remains to Be Done -- Appendix: What Women Should Know about Current Treatments.".
• catalog title "Breakthrough : the race to find the breast cancer gene / Kevin Davies, Michael White.".
• catalog title "Race to find the breast cancer gene".
• catalog type "text".