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• catalog abstract "This book is the compilation of presentations from a conference on the titled topic. The vast majority of reports present descriptive results, but unfortunately, some of the work appears to have been done with somewhat marginal or obsolescent immunomethodology. The primary audience for this book is those interested in drug abuse and HIV infection. Neuroendocrine immunologists are a secondary audience. An unwritten rule is violated in several chapters. In one there are three times as many authors (25) as there are text pages (8)! Neuroendoimmunology is a rapidly mushrooming and highly relevant field. Many investigators, until recently, have been operating at the periphery of the immunology mainstream (not always by choice), but it is critical that this field now undergoes the same strict scrutiny that other immunobiologic subfields have and are undergoing. The implications that drugs of abuse may somehow facilitate infection with HIV is extraordinarily relevant. Unfortunately, after reading these proceedings, the topic still remains enigmatic. In fact, the most valuable chapter in this book is the last one -- a summary of the panel discussion of this conference where it is explicitly stated that it is still not known definitively whether drugs of abuse have a role in accelerating the course of the HIV disease. This book serves as a focused source of conference papers on an important topic; one hopes that subsequent conferences will move the subject further ahead and provide definitive evidence for or against the interconnection of HIV and drugs of abuse. Parenthetically, some of the most important nuggets of information in this book are actually not related to the latter butare more relevant to the rapidly increasing understanding of the connections between neuroendocrine receptors and immune responses in general.".
• catalog contributor b9983380.
• catalog contributor b9983381.
• catalog contributor b9983382.
• catalog created "c1996.".
• catalog date "1996".
• catalog date "c1996.".
• catalog dateCopyrighted "c1996.".
• catalog description "1. AIDS, Drugs of Abuse and the Neuroimmune Axis: Introduction and Perspectives / Herman Friedman -- 2. The Effect of Novel Opioids on Natural Killer Activity and Tumor Surveillance in Vivo / Daniel J. J. Carr, Mace Scott, Linda L. Brockunier, Jerome R. Bagely and Charles P. France -- 3. Kappa Opioid Receptors on Immune Cells as Studied by Fluorescent Ligands / Jean M. Bidlack, Diane M. P. Lawrence and Tracey A. Ignatowski -- 4. Presence of Opiate Alkaloid-Selective [actual symbol not reproducible] Receptors in Cultured Astrocytes and in Brain and Retina / M. H. Makman, K. Dobrenis, S. Downie, W. D. Lyman and B. Dvorkin -- 5. Opiates, Glia, and Neurotoxicity / Chun C. Chao, Shuxian Hu and Philip K. Peterson -- 6. Morphine Affects the Brain-Immune Axis by Modulating an Interleukin - Beta Dependent Pathway / Sulie L. Chang, Roberta L. Moldow, Steve D. House and James E. Zadina.".
• catalog description "Includes bibliographical references and index.".
• catalog description "This book is the compilation of presentations from a conference on the titled topic. The vast majority of reports present descriptive results, but unfortunately, some of the work appears to have been done with somewhat marginal or obsolescent immunomethodology. The primary audience for this book is those interested in drug abuse and HIV infection. Neuroendocrine immunologists are a secondary audience. An unwritten rule is violated in several chapters. In one there are three times as many authors (25) as there are text pages (8)! Neuroendoimmunology is a rapidly mushrooming and highly relevant field. Many investigators, until recently, have been operating at the periphery of the immunology mainstream (not always by choice), but it is critical that this field now undergoes the same strict scrutiny that other immunobiologic subfields have and are undergoing. The implications that drugs of abuse may somehow facilitate infection with HIV is extraordinarily relevant. Unfortunately, after reading these proceedings, the topic still remains enigmatic. In fact, the most valuable chapter in this book is the last one -- a summary of the panel discussion of this conference where it is explicitly stated that it is still not known definitively whether drugs of abuse have a role in accelerating the course of the HIV disease. This book serves as a focused source of conference papers on an important topic; one hopes that subsequent conferences will move the subject further ahead and provide definitive evidence for or against the interconnection of HIV and drugs of abuse. Parenthetically, some of the most important nuggets of information in this book are actually not related to the latter butare more relevant to the rapidly increasing understanding of the connections between neuroendocrine receptors and immune responses in general.".
• catalog extent "xi, 234 p. :".
• catalog identifier "0306453754".
• catalog isPartOf "Advances in experimental medicine and biology ; v. 402".
• catalog issued "1996".
• catalog issued "c1996.".
• catalog language "eng".
• catalog publisher "New York : Plenum Press,".
• catalog subject "616.97/92071 20".
• catalog subject "AIDS (Disease) Etiology Congresses.".
• catalog subject "AIDS (Disease) Risk factors Congresses.".
• catalog subject "Acquired Immunodeficiency Syndrome immunology congresses.".
• catalog subject "Drug abuse Immunological aspects Congresses.".
• catalog subject "Drugs of abuse Immunology Congresses.".
• catalog subject "Immune System drug effects congresses.".
• catalog subject "Immune System immunology Congresses.".
• catalog subject "Immunosuppression Congresses.".
• catalog subject "Immunosuppression congresses.".
• catalog subject "Neuroimmunology Congresses.".
• catalog subject "Neuroimmunomodulation drug effects congresses.".
• catalog subject "Neuroimmunomodulation immunology Congresses.".
• catalog subject "RC607.A26 A3457337 1996".
• catalog subject "Street Drugs congresses.".
• catalog subject "Street Drugs immunology Congresses.".
• catalog subject "Substance-Related Disorders complications congresses.".
• catalog subject "Substance-Related Disorders immunology Congresses.".
• catalog subject "W1 AD559 v.402 1996 QW 504 A288 1996".
• catalog tableOfContents "1. AIDS, Drugs of Abuse and the Neuroimmune Axis: Introduction and Perspectives / Herman Friedman -- 2. The Effect of Novel Opioids on Natural Killer Activity and Tumor Surveillance in Vivo / Daniel J. J. Carr, Mace Scott, Linda L. Brockunier, Jerome R. Bagely and Charles P. France -- 3. Kappa Opioid Receptors on Immune Cells as Studied by Fluorescent Ligands / Jean M. Bidlack, Diane M. P. Lawrence and Tracey A. Ignatowski -- 4. Presence of Opiate Alkaloid-Selective [actual symbol not reproducible] Receptors in Cultured Astrocytes and in Brain and Retina / M. H. Makman, K. Dobrenis, S. Downie, W. D. Lyman and B. Dvorkin -- 5. Opiates, Glia, and Neurotoxicity / Chun C. Chao, Shuxian Hu and Philip K. Peterson -- 6. Morphine Affects the Brain-Immune Axis by Modulating an Interleukin - Beta Dependent Pathway / Sulie L. Chang, Roberta L. Moldow, Steve D. House and James E. Zadina.".
• catalog title "AIDS, drugs of abuse, and the neuroimmune axis / edited by Herman Friedman ... [et al.].".
• catalog type "text".