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- catalog abstract "The 26 invited and contributed papers explore the relationship between in-vitro and in-vivo reactions to extended release drugs, especially as they relate to determining sufficient and safe dosage. Among the topics are the theory and case studies of dissolution assay development, a general framework for various types of deconvolution methods, determining critical manufacturing and formation variables for a hydrophilic matrix tablet formulation using an in-vitro discriminatory dissolution method, a comparison of methodologies for evaluating regional intestinal permeability, and the impact of correlations on product development and regulatory agencies.".
- catalog contributor b10480305.
- catalog contributor b10480306.
- catalog contributor b10480307.
- catalog created "c1997.".
- catalog date "1997".
- catalog date "c1997.".
- catalog dateCopyrighted "c1997.".
- catalog description "Examples of in vitro-in vivo relationships with a diverse range of quality -- Dissolution assay development for in vitro-in vivo correlations: theory and case studies -- In vitro dissolution profile comparison and IVIVR: carbamazepine case -- A general framework for non-parametric subject-specific and population deconvolution methods for in vivo-in vitro correlation -- Convolutin-based approaches for in vivo-in vitro correlation modeling -- Approaches to IVIVR modelling and statistical analysis -- Validation of in vitro-in vivo correlation models -- Examples of developing in vitro-in vivo relationships -- The biopharmaceutic drug classification and drugs administered in extended release (ER) formulations -- Investigating in vitro drug release mechanisms inside dosage forms: monitoring liquid ingress in HPMC hydrophilic matrices using confocal microscopy -- Determinatin of critical manufacturing and formulatin variables for a hydrophilic matrix tablet formulatin using an in vitro discriminatroy dissolution method -- Artificial neural network based in vitro-in vivo correlations -- Setting dissolution specificatins for modified-release dosage forms -- Review of methodologies for the comparison of dissolution profile data -- Assessing whether controlled release products with differing in vitro dissolution rates have the same in vivo-in vitro relationship -- Comparison of methodologies for evaluating regional intestinal permeability -- In vitro-in vivo relationships of several "immediate" release tablets -- Nonlinear in vitro-in vivo correlations -- Use of nonlinear mixed".
- catalog description "Includes bibliographical references and index.".
- catalog description "The 26 invited and contributed papers explore the relationship between in-vitro and in-vivo reactions to extended release drugs, especially as they relate to determining sufficient and safe dosage. Among the topics are the theory and case studies of dissolution assay development, a general framework for various types of deconvolution methods, determining critical manufacturing and formation variables for a hydrophilic matrix tablet formulation using an in-vitro discriminatory dissolution method, a comparison of methodologies for evaluating regional intestinal permeability, and the impact of correlations on product development and regulatory agencies.".
- catalog extent "ix, 300 p. :".
- catalog hasFormat "In vitro-in vivo correlations.".
- catalog identifier "0306456001".
- catalog isFormatOf "In vitro-in vivo correlations.".
- catalog isPartOf "Advances in experimental medicine and biology ; v. 423".
- catalog issued "1997".
- catalog issued "c1997.".
- catalog language "eng".
- catalog publisher "New York : Plenum Press,".
- catalog relation "In vitro-in vivo correlations.".
- catalog subject "615/.19 21".
- catalog subject "Biological Availability Congresses.".
- catalog subject "Dosage Forms congresses.".
- catalog subject "Drug Evaluation, Preclinical congresses.".
- catalog subject "Drug Evaluation, Preclinical methods Congresses.".
- catalog subject "Drugs Bioavailability Testing.".
- catalog subject "Drugs Solubility Testing.".
- catalog subject "QV 771 I348 1997".
- catalog subject "RS189 .I438 1997".
- catalog subject "Solubility congresses.".
- catalog subject "W1 AD559 v.423 1997".
- catalog tableOfContents "Examples of in vitro-in vivo relationships with a diverse range of quality -- Dissolution assay development for in vitro-in vivo correlations: theory and case studies -- In vitro dissolution profile comparison and IVIVR: carbamazepine case -- A general framework for non-parametric subject-specific and population deconvolution methods for in vivo-in vitro correlation -- Convolutin-based approaches for in vivo-in vitro correlation modeling -- Approaches to IVIVR modelling and statistical analysis -- Validation of in vitro-in vivo correlation models -- Examples of developing in vitro-in vivo relationships -- The biopharmaceutic drug classification and drugs administered in extended release (ER) formulations -- Investigating in vitro drug release mechanisms inside dosage forms: monitoring liquid ingress in HPMC hydrophilic matrices using confocal microscopy -- Determinatin of critical manufacturing and formulatin variables for a hydrophilic matrix tablet formulatin using an in vitro discriminatroy dissolution method -- Artificial neural network based in vitro-in vivo correlations -- Setting dissolution specificatins for modified-release dosage forms -- Review of methodologies for the comparison of dissolution profile data -- Assessing whether controlled release products with differing in vitro dissolution rates have the same in vivo-in vitro relationship -- Comparison of methodologies for evaluating regional intestinal permeability -- In vitro-in vivo relationships of several "immediate" release tablets -- Nonlinear in vitro-in vivo correlations -- Use of nonlinear mixed".
- catalog title "In vitro-in vivo correlations / edited by David Young, John G. Devane, and Jackie Butler.".
- catalog type "text".