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catalog contributor b10903679.
catalog contributor b10903680.
catalog created "c1998.".
catalog date "1998".
catalog date "c1998.".
catalog dateCopyrighted "c1998.".
catalog description "Automation of Combinatorial Chemistry for Large Libraries / Michael Needels and Jeffrey Sugarman -- 18. Analytical Chemistry Issues in Combinatorial Organic Synthesis / William L. Fitch, Gary C. Look and George Detre -- 19. Quantifying Diversity / Yvonne C. Martin, Robert D. Brown and Mark G. Bures -- Pt. IV. Biological Diversity -- 20. Protein Scaffolds for Peptide Libraries / Ronald H. Hoess -- 21. Combinatorial Biosynthesis of "Unnatural" Natural Products / Chaitan Khosla -- Pt. V. Screening -- 22. Strategies for Screening Combinatorial Libraries / Bruce A. Beutel -- 23. Approaches and Technologies for Screening Large Combinatorial Libraries / Nolan H. Sigal and Daniel Chelsky -- Pt. VI. Combinatorial Drug Screening and Development -- 24. Combinatorial Drug Discovery: Concepts / Judd Berman and Russell J. Howard -- 25. ADME/PK Assays in Screening for Orally Active Drug Candidates /".
catalog description "Foreword: Combinatorial Chemistry at a Crossroads / Walter H. Moos -- Pt. I. Combinatorial Chemistry and Molecular Diversity: An Introduction -- 1. Historical Overview of the Developing Field of Molecular Diversity / John C. Chabala -- 2. Strategies in the Design and Synthesis of Chemical Libraries / Eric M. Gordon -- 3. Solid-Phase Peptide Synthesis, Lead Generation, and Optimization / Bruce Seligman, Michael Lebl and Kit S. Lam -- 4. Light-Directed Chemical Synthesis of Positionally Encoded Peptide Arrays / Jeffrey W. Jacobs, Dinesh V. Patel and Zhengyu Yuan -- 5. Conformationally Restricted Peptide and Peptidomimetic Libraries / Alex A. Virgilio and Jonathan A. Ellman -- 6. Submonomer Approaches for the Generation of Molecular Diversity: Nonnatural Oligomer and Organic Template Libraries / Lutz S. Richter, Dane A. Goff and Kerry L. Spear -- 7. Oligonucleotide Libraries as a Source of Molecular Diversity /".
catalog description "Houng-Yau Mei and Anthony Czarnik -- Pt. II. Small Molecule Libraries -- 8. Small Molecule Libraries: Overview of Issues and Strategies in Library Design / John J. Baldwin -- 9. Protease Inhibitor Libraries / Dinesh V. Patel and David A. Campbell -- 10. Heterocyclic Combinatorial Chemistry: Azine and Diazepine Pharmacophores / Mikhail F. Gordeev and Dinesh V. Patel -- 11. Scaffolds for Small Molecule Libraries / Michael R. Pavia -- 12. Application of Combinatorial Chemistry to Biopolymers / Edmund J. Moran -- 13. Oligosaccharide and Glycoconjugate Solid-Phase Synthesis Technologies for Drug Discovery / Michael J. Sofia -- 14. Encoded Combinatorial Chemistry / Jeffrey W. Jacobs and Zhi-Jie Ni -- 15. Parallel Organic Synthesis in Array Format / Steven E. Hall -- 16. Synthetic Organic Chemistry on Solid Support / Stephen W. Kaldor and Miles G. Siegel -- Pt. III. Automation, Analytical, and Computational Methods -- 17.".
catalog description "Includes bibliographical references and index.".
catalog description "Jacqueline A. Gibbans, Eric W. Taylor and Rene A. Braeckman -- 26. Combinatorial Technologies: Prospects and Future Issues / James F. Kerwin, Jr. -- 27. Appendix: Combinatorial Chemistry Information Management / David Weininger.".
catalog extent "xxiv, 516 p.".
catalog hasFormat "Combinatorial chemistry and molecular diversity in drug discovery.".
catalog identifier "0471155187 (cloth : alk. paper)".
catalog isFormatOf "Combinatorial chemistry and molecular diversity in drug discovery.".
catalog issued "1998".
catalog issued "c1998.".
catalog language "eng".
catalog publisher "New York : Wiley-Liss,".
catalog relation "Combinatorial chemistry and molecular diversity in drug discovery.".
catalog subject "1998 J-945".
catalog subject "615/.19 21".
catalog subject "Chemistry, Pharmaceutical.".
catalog subject "Combinatorial chemistry.".
catalog subject "Drug Design.".
catalog subject "Drugs Design.".
catalog subject "QV 744 C7315 1998".
catalog subject "RS419 .C656 1998".
catalog tableOfContents "Automation of Combinatorial Chemistry for Large Libraries / Michael Needels and Jeffrey Sugarman -- 18. Analytical Chemistry Issues in Combinatorial Organic Synthesis / William L. Fitch, Gary C. Look and George Detre -- 19. Quantifying Diversity / Yvonne C. Martin, Robert D. Brown and Mark G. Bures -- Pt. IV. Biological Diversity -- 20. Protein Scaffolds for Peptide Libraries / Ronald H. Hoess -- 21. Combinatorial Biosynthesis of "Unnatural" Natural Products / Chaitan Khosla -- Pt. V. Screening -- 22. Strategies for Screening Combinatorial Libraries / Bruce A. Beutel -- 23. Approaches and Technologies for Screening Large Combinatorial Libraries / Nolan H. Sigal and Daniel Chelsky -- Pt. VI. Combinatorial Drug Screening and Development -- 24. Combinatorial Drug Discovery: Concepts / Judd Berman and Russell J. Howard -- 25. ADME/PK Assays in Screening for Orally Active Drug Candidates /".
catalog tableOfContents "Foreword: Combinatorial Chemistry at a Crossroads / Walter H. Moos -- Pt. I. Combinatorial Chemistry and Molecular Diversity: An Introduction -- 1. Historical Overview of the Developing Field of Molecular Diversity / John C. Chabala -- 2. Strategies in the Design and Synthesis of Chemical Libraries / Eric M. Gordon -- 3. Solid-Phase Peptide Synthesis, Lead Generation, and Optimization / Bruce Seligman, Michael Lebl and Kit S. Lam -- 4. Light-Directed Chemical Synthesis of Positionally Encoded Peptide Arrays / Jeffrey W. Jacobs, Dinesh V. Patel and Zhengyu Yuan -- 5. Conformationally Restricted Peptide and Peptidomimetic Libraries / Alex A. Virgilio and Jonathan A. Ellman -- 6. Submonomer Approaches for the Generation of Molecular Diversity: Nonnatural Oligomer and Organic Template Libraries / Lutz S. Richter, Dane A. Goff and Kerry L. Spear -- 7. Oligonucleotide Libraries as a Source of Molecular Diversity /".
catalog tableOfContents "Houng-Yau Mei and Anthony Czarnik -- Pt. II. Small Molecule Libraries -- 8. Small Molecule Libraries: Overview of Issues and Strategies in Library Design / John J. Baldwin -- 9. Protease Inhibitor Libraries / Dinesh V. Patel and David A. Campbell -- 10. Heterocyclic Combinatorial Chemistry: Azine and Diazepine Pharmacophores / Mikhail F. Gordeev and Dinesh V. Patel -- 11. Scaffolds for Small Molecule Libraries / Michael R. Pavia -- 12. Application of Combinatorial Chemistry to Biopolymers / Edmund J. Moran -- 13. Oligosaccharide and Glycoconjugate Solid-Phase Synthesis Technologies for Drug Discovery / Michael J. Sofia -- 14. Encoded Combinatorial Chemistry / Jeffrey W. Jacobs and Zhi-Jie Ni -- 15. Parallel Organic Synthesis in Array Format / Steven E. Hall -- 16. Synthetic Organic Chemistry on Solid Support / Stephen W. Kaldor and Miles G. Siegel -- Pt. III. Automation, Analytical, and Computational Methods -- 17.".
catalog tableOfContents "Jacqueline A. Gibbans, Eric W. Taylor and Rene A. Braeckman -- 26. Combinatorial Technologies: Prospects and Future Issues / James F. Kerwin, Jr. -- 27. Appendix: Combinatorial Chemistry Information Management / David Weininger.".
catalog title "Combinatorial chemistry and molecular diversity in drug discovery / edited by Eric M. Gordon and James F. Kerwin., Jr.".
catalog type "text".