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- catalog abstract "Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.".
- catalog contributor b11694331.
- catalog contributor b11694332.
- catalog contributor b11694333.
- catalog created "c2000.".
- catalog date "2000".
- catalog date "c2000.".
- catalog dateCopyrighted "c2000.".
- catalog description "Includes bibliographical references and index.".
- catalog description "Membrane Ectopeptidases with Influence on Immune Functions -- Review: The Role of Membrane Peptidases in Immune Functions / Uwe Lendeckel, Thilo Kahne, Dagmar Riemann, Klaus Neubert, Marco Arndt, Dirk Reinhold -- Structure and Function of Aminopeptidase N / Hans Sjostrom, Ove Noren, Jorgen Olsen -- Modulation of WNT-5a Expression by Actinonin: Linkage of APN to the WNT-Pathway? / Uwe Lendeckel, Marco Arndt, Karin Frank, Antje Spiess, Dirk Reinhold, Siegfried Ansorge -- Enzymatic Activity is not a Precondition for the Intracellular Calcium Increase Mediated by mAbs Specific for Aminopeptidase N/CD13 / Alexander Navarrete Santos, Jurgen Langner, Dagmar Riemann -- Transforming Growth Factor-[beta] Increases the Expression of Aminopeptidase N/CD13 mRNA and Protein in Monocytes and Monocytic Cell Lines / Astrid Kehlen, Jurgen Langner, Dagmar Riemann -- Cell-Cell Contact Between Lymphocytes and Fibroblast-like Synoviocytes Induces Lymphocytic Expression of Aminopeptidase N/CD13 and Results in Lymphocytic Activation / Dagmar Riemann, Jana Rontsch, Bettina Hause, Jurgen Langner, Astrid Kehlen -- Natural Substrates of Dipeptidyl Peptidase IV / Ingrid De Meester, Christine Durinx, Gunther Bal, Paul Proost, Sofie Struyf, Filip Goossens, Koen Augustyns, Simon Scharpe -- Relating Structure to Function in the Beta-Propeller Domain of Dipeptidyl Peptidase IV: Point Mutations that Influence Adenosine Deaminase Binding, Antibody Binding and Enzyme Activity / Mark D. Gorrell, Catherine A. Abbott, Thilo Kahne, Miriam T. Levy, W. Bret Church, Geoffrey W. McCaughan.".
- catalog description "Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.".
- catalog extent "xii, 522 p. :".
- catalog identifier "0306463830".
- catalog isPartOf "Advances in experimental medicine and biology ; v. 477".
- catalog issued "2000".
- catalog issued "c2000.".
- catalog language "eng".
- catalog publisher "New York : Kluwer Academic/Plenum,".
- catalog subject "616.07/9 21".
- catalog subject "Endopeptidases Immunology Congresses.".
- catalog subject "Endopeptidases Pathophysiology Congresses.".
- catalog subject "Peptidase Immunology Congresses.".
- catalog subject "Peptidase Pathophysiology Congresses.".
- catalog subject "Peptide Hydrolases immunology Congresses.".
- catalog subject "Peptide Hydrolases immunology".
- catalog subject "Peptide Hydrolases physiology Congresses.".
- catalog subject "Peptide Hydrolases physiology".
- catalog subject "QP609.P45 C452 2000".
- catalog subject "QU 136 C3935 2000".
- catalog subject "W1 AD559 v.477 2000".
- catalog tableOfContents "Membrane Ectopeptidases with Influence on Immune Functions -- Review: The Role of Membrane Peptidases in Immune Functions / Uwe Lendeckel, Thilo Kahne, Dagmar Riemann, Klaus Neubert, Marco Arndt, Dirk Reinhold -- Structure and Function of Aminopeptidase N / Hans Sjostrom, Ove Noren, Jorgen Olsen -- Modulation of WNT-5a Expression by Actinonin: Linkage of APN to the WNT-Pathway? / Uwe Lendeckel, Marco Arndt, Karin Frank, Antje Spiess, Dirk Reinhold, Siegfried Ansorge -- Enzymatic Activity is not a Precondition for the Intracellular Calcium Increase Mediated by mAbs Specific for Aminopeptidase N/CD13 / Alexander Navarrete Santos, Jurgen Langner, Dagmar Riemann -- Transforming Growth Factor-[beta] Increases the Expression of Aminopeptidase N/CD13 mRNA and Protein in Monocytes and Monocytic Cell Lines / Astrid Kehlen, Jurgen Langner, Dagmar Riemann -- Cell-Cell Contact Between Lymphocytes and Fibroblast-like Synoviocytes Induces Lymphocytic Expression of Aminopeptidase N/CD13 and Results in Lymphocytic Activation / Dagmar Riemann, Jana Rontsch, Bettina Hause, Jurgen Langner, Astrid Kehlen -- Natural Substrates of Dipeptidyl Peptidase IV / Ingrid De Meester, Christine Durinx, Gunther Bal, Paul Proost, Sofie Struyf, Filip Goossens, Koen Augustyns, Simon Scharpe -- Relating Structure to Function in the Beta-Propeller Domain of Dipeptidyl Peptidase IV: Point Mutations that Influence Adenosine Deaminase Binding, Antibody Binding and Enzyme Activity / Mark D. Gorrell, Catherine A. Abbott, Thilo Kahne, Miriam T. Levy, W. Bret Church, Geoffrey W. McCaughan.".
- catalog title "Cellular peptidases in immune functions and diseases 2 / edited by Jürgen Langner and Siegfried Ansorge.".
- catalog type "Congresses".
- catalog type "text".