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- catalog abstract ""The authors use the real chemical history of the development of drugs from several therapeutic areas as detailed case studies, each chosen to illustrate a range of issues and methodologies in industrial chemistry. Several chapters cover the development of the various [Beta]-lactam antibiotics; two chapters describe the discovery and synthesis of the anticancer drugs Idarubicin and Paclitaxal; in another chapter, the synthesis of the anti-viral drug Acyclovir and the 'patent war' that resulted are explored." "Between them, the authors represent considerable first-hand experience in pharmaceutical research and development. The technical, practical, and strategic information they have amassed make this essential reading for graduate and undergraduate chemists intending to work in the pharmaceutical industry, as well as for industrial chemists themselves. Lecturers teaching courses in medicinal and organic chemistry will also find it useful."--Jacket.".
- catalog contributor b11995255.
- catalog contributor b11995256.
- catalog created "c2000.".
- catalog date "2000".
- catalog date "c2000.".
- catalog dateCopyrighted "c2000.".
- catalog description ""The authors use the real chemical history of the development of drugs from several therapeutic areas as detailed case studies, each chosen to illustrate a range of issues and methodologies in industrial chemistry. Several chapters cover the development of the various [Beta]-lactam antibiotics; two chapters describe the discovery and synthesis of the anticancer drugs Idarubicin and Paclitaxal; in another chapter, the synthesis of the anti-viral drug Acyclovir and the 'patent war' that resulted are explored." "Between them, the authors represent considerable first-hand experience in pharmaceutical research and development. The technical, practical, and strategic information they have amassed make this essential reading for graduate and undergraduate chemists intending to work in the pharmaceutical industry, as well as for industrial chemists themselves. Lecturers teaching courses in medicinal and organic chemistry will also find it useful."--Jacket.".
- catalog description "1. Process research and development: the modern approach -- 2. Nonclassical [beta]-lactam antibiotics -- 3. Thienamycin-Imipenem -- 4. Sanfetrinems -- 5. Ritipenems -- 6. Losartan -- 7. Nabumetone -- 8. Acyclovir -- 9. Ibarubicin -- 10. Paclitaxel -- 11. The drug discovery process: towards a new paradigm.".
- catalog description "Includes bibliographical references and index.".
- catalog extent "xvi, 266 p. :".
- catalog identifier "0198503830 (pbk.)".
- catalog identifier "0198503849 (hbk)".
- catalog issued "2000".
- catalog issued "c2000.".
- catalog language "eng".
- catalog publisher "Oxford : New York : Oxford University Press,".
- catalog subject "2001 C-067".
- catalog subject "615/.19 21".
- catalog subject "Chemistry, Pharmaceutical.".
- catalog subject "Drug Industry.".
- catalog subject "Drug development.".
- catalog subject "Pharmaceutical Preparations chemical synthesis.".
- catalog subject "Pharmaceutical chemistry.".
- catalog subject "QV 736 C117f 2000".
- catalog subject "RS403 .C23 2000".
- catalog tableOfContents "1. Process research and development: the modern approach -- 2. Nonclassical [beta]-lactam antibiotics -- 3. Thienamycin-Imipenem -- 4. Sanfetrinems -- 5. Ritipenems -- 6. Losartan -- 7. Nabumetone -- 8. Acyclovir -- 9. Ibarubicin -- 10. Paclitaxel -- 11. The drug discovery process: towards a new paradigm.".
- catalog title "From bench to market : the evolution of chemical synthesis / by Walter Cabri and Romano DiFabio.".
- catalog type "text".