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- catalog abstract ""Corepressors are newly discovered assemblies of proteins that play essential roles in eukaryotic gene regulation. Recent discoveries about corepressors have provided new insights into the molecular basis of gene regulation, and have established surprising connections between the mechanisms of action of a wide variety of transcriptional regulators. The reviews in this volume critically discuss the nature, mechanisms of action, and physiological roles of corepressors in a diverse assortment of biological systems. Both basic and clinical investigators should be able to find relevant information. The comprehensive nature of the compilation, and the breadth of the reviews, are intended to provide the reader with an excellent introduction to the newly emergent and rapidly growing field of corepressor research, and a valuable and detailed reference guide."--Jacket.".
- catalog contributor b12020217.
- catalog created "c2001.".
- catalog date "2001".
- catalog date "c2001.".
- catalog dateCopyrighted "c2001.".
- catalog description ""Corepressors are newly discovered assemblies of proteins that play essential roles in eukaryotic gene regulation. Recent discoveries about corepressors have provided new insights into the molecular basis of gene regulation, and have established surprising connections between the mechanisms of action of a wide variety of transcriptional regulators. The reviews in this volume critically discuss the nature, mechanisms of action, and physiological roles of corepressors in a diverse assortment of biological systems. Both basic and clinical investigators should be able to find relevant information. The comprehensive nature of the compilation, and the breadth of the reviews, are intended to provide the reader with an excellent introduction to the newly emergent and rapidly growing field of corepressor research, and a valuable and detailed reference guide."--Jacket.".
- catalog description "Includes bibliographical references and index.".
- catalog description "Molecular mechanisms of corepressor function / F.D. Urnov, A.P. Wolffe, and D. Guschin -- Role of histone deacetylase complexes in the regulation of chromatin metabolism / A. Kuzmichev and D. Reinberg -- Corepressor proteins and control of transcription in yeast / J.R. Bone and S.Y. Roth -- Corepressor proteins in Drosophila development / M. Mannervik -- Corepressors and nuclear hormone receptor function / P. Ordentlich, M. Downes, and R.M. Evans -- Regulation of SMRT and N-CoR corepressor function / M.L. Privalsky -- Corepressors and retinoblastoma protein function / J.W. Harbour and D.C. Dean -- Smad transcriptional corepressors in TGF[beta] family signaling / D. Wotton and J. Massague -- Role of nuclear receptor corepressors in leukemogenesis / F. Guidez and A. Zelent.".
- catalog extent "ix, 190 p. :".
- catalog identifier "3540676112".
- catalog isPartOf "Current topics in microbiology and immunology, 0070-217X ; 254".
- catalog issued "2001".
- catalog issued "c2001.".
- catalog language "eng".
- catalog publisher "Berlin ; New York : Springer-Verlag,".
- catalog subject "Gene Expression Regulation".
- catalog subject "Gene expression.".
- catalog subject "Genes.".
- catalog subject "Genetic regulation.".
- catalog subject "Genetic transcription Regulation.".
- catalog subject "Molecular genetics.".
- catalog subject "Promoters (Genetics)".
- catalog subject "QH 450 T7716 2001".
- catalog subject "QR1 .E6 v.254".
- catalog subject "Repressor Proteins.".
- catalog subject "Transcription, Genetic.".
- catalog subject "W1 CU82K v.254 2001".
- catalog tableOfContents "Molecular mechanisms of corepressor function / F.D. Urnov, A.P. Wolffe, and D. Guschin -- Role of histone deacetylase complexes in the regulation of chromatin metabolism / A. Kuzmichev and D. Reinberg -- Corepressor proteins and control of transcription in yeast / J.R. Bone and S.Y. Roth -- Corepressor proteins in Drosophila development / M. Mannervik -- Corepressors and nuclear hormone receptor function / P. Ordentlich, M. Downes, and R.M. Evans -- Regulation of SMRT and N-CoR corepressor function / M.L. Privalsky -- Corepressors and retinoblastoma protein function / J.W. Harbour and D.C. Dean -- Smad transcriptional corepressors in TGF[beta] family signaling / D. Wotton and J. Massague -- Role of nuclear receptor corepressors in leukemogenesis / F. Guidez and A. Zelent.".
- catalog title "Transcriptional corepressors : mediators of eukaryotic gene repression / edited by Martin L. Privalsky.".
- catalog type "text".