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- catalog abstract ""Peptide Nucleic Acid (PNA) is a powerful new biomolecular tool with a wide range of important applications. PNA mimics the behaviour of DNA and binds complementary nucleic acid strands. The unique chemical, physical and biological properties of PNA have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors." "This book contains state-of-the-art protocols and applications on all aspects of PNA. An essential text for all molecular biologists, microbiologists, biochemists, geneticists, biotechnologists and nucleic acid chemists wishing to keep up with the latest developments."--Jacket.".
- catalog contributor b12217003.
- catalog contributor b12217004.
- catalog created "c1999.".
- catalog date "1999".
- catalog date "c1999.".
- catalog dateCopyrighted "c1999.".
- catalog description ""Peptide Nucleic Acid (PNA) is a powerful new biomolecular tool with a wide range of important applications. PNA mimics the behaviour of DNA and binds complementary nucleic acid strands. The unique chemical, physical and biological properties of PNA have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors." "This book contains state-of-the-art protocols and applications on all aspects of PNA. An essential text for all molecular biologists, microbiologists, biochemists, geneticists, biotechnologists and nucleic acid chemists wishing to keep up with the latest developments."--Jacket.".
- catalog description "An introduction to PNA / Peter E. Nielsen, Michael Egholm -- Synthesis of PNA oligomers by Fmoc chemistry / Ralph Casae, Ivar S. Jenson, Michael Egholm -- PNA-DNA chimeras -- Synthesis of PNA-DNA chimera by MMT chemistry / Ravi Vinyak -- Labelling of PNA / Henrik Ørum, Ralph Casael, Michael Egholm -- Thermodynamics of PNA-nucleic acid interactions / Anders Holmén, Bengt Nordén -- Application of peptide nucleic acid probes for in situ hybridization / M. Thisted [and others] -- PNA-arrays for nucleic acid detection / S. Matsiak [and others] -- PNA blocker probes enhance specificity in probe assays / Mark J. fiandaca, Jens J. Hyldig-Nielsen, James M. Coull -- MALDI-TOF mass spectrometric detection of PNA hybrids for genetic analysis / Timothy J. Griffin, Wei Tang, Lloyd M. Smith -- PNA biosensors for nucleic acid detection / Joseph Wang -- PNA directed genome rare cutting / Vadim V. Demidov, Maxim d. Frank-Kamenetskii -- Duplex DNA capture / Vadim V. Demidov, Nikolay O. Bukanov, Maxim D. Frank-Kamenetskii -- Purification of nucleic acids by hybridization to affinity tagged PNA probes / Henrik Ørum -- Plasmid labeling using PNA / Xiaowu Liang [and others] -- Antisense effects in Escherichia coli / Liam Good, Peter E. Nielsen -- Characterization of PNA-dsDNA strand displacement complexes / H. Jakob Larsen, Peter E. Nielsen -- Interactions of peptide nucleic acids with DNA processing enzymes / Kevin D. Raney, Susan E. Hamilton, David R. Corey.".
- catalog description "Includes bibliographical references and index.".
- catalog extent "x, 266 p. :".
- catalog hasFormat "Peptide nucleic acids.".
- catalog identifier "1898486166".
- catalog isFormatOf "Peptide nucleic acids.".
- catalog issued "1999".
- catalog issued "c1999.".
- catalog language "eng".
- catalog publisher "Wymondham : Horizen Scientific,".
- catalog relation "Peptide nucleic acids.".
- catalog subject "2000 N-304".
- catalog subject "572.8 21".
- catalog subject "Nucleic acids.".
- catalog subject "Peptide Nucleic Acids.".
- catalog subject "QP620 .P46 1999".
- catalog subject "QU 58 P424 1999".
- catalog tableOfContents "An introduction to PNA / Peter E. Nielsen, Michael Egholm -- Synthesis of PNA oligomers by Fmoc chemistry / Ralph Casae, Ivar S. Jenson, Michael Egholm -- PNA-DNA chimeras -- Synthesis of PNA-DNA chimera by MMT chemistry / Ravi Vinyak -- Labelling of PNA / Henrik Ørum, Ralph Casael, Michael Egholm -- Thermodynamics of PNA-nucleic acid interactions / Anders Holmén, Bengt Nordén -- Application of peptide nucleic acid probes for in situ hybridization / M. Thisted [and others] -- PNA-arrays for nucleic acid detection / S. Matsiak [and others] -- PNA blocker probes enhance specificity in probe assays / Mark J. fiandaca, Jens J. Hyldig-Nielsen, James M. Coull -- MALDI-TOF mass spectrometric detection of PNA hybrids for genetic analysis / Timothy J. Griffin, Wei Tang, Lloyd M. Smith -- PNA biosensors for nucleic acid detection / Joseph Wang -- PNA directed genome rare cutting / Vadim V. Demidov, Maxim d. Frank-Kamenetskii -- Duplex DNA capture / Vadim V. Demidov, Nikolay O. Bukanov, Maxim D. Frank-Kamenetskii -- Purification of nucleic acids by hybridization to affinity tagged PNA probes / Henrik Ørum -- Plasmid labeling using PNA / Xiaowu Liang [and others] -- Antisense effects in Escherichia coli / Liam Good, Peter E. Nielsen -- Characterization of PNA-dsDNA strand displacement complexes / H. Jakob Larsen, Peter E. Nielsen -- Interactions of peptide nucleic acids with DNA processing enzymes / Kevin D. Raney, Susan E. Hamilton, David R. Corey.".
- catalog title "Peptide nucleic acids : protocols and applications / edited by Peter E. Nielsen and Michael Egholm.".
- catalog type "text".