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• catalog abstract "Expert practitioners present a comprehensive approach to vaccine development, production, and assessment that can be adapted successfully to any vaccine. Recent advances in vaccine research include those in the areas of bacterial genomics, antigen-specific T Cell quantification, genetic manipulation of vaccine vectors, the harnessing of natural molecules concerned with the regulation of immune responses, and the burgeoning field of DNA vaccinology. This second edition has been thoroughly revised with new chapters on live viral vaccine vectors, attenuated bacterial vectors, immunomodulators, MHC-peptide tetrameric complexes and the identification of vaccine candidates by genomic analysis. Additionally, chapters from the first edition have been updated to accommodate state-of-the-art methods in molecular vaccinology, making this a valuable and relevant practical manual for all those seeking to produce improved or novel vaccines.".
• catalog contributor b12958489.
• catalog contributor b12958490.
• catalog contributor b12958491.
• catalog contributor b12958492.
• catalog contributor b12958493.
• catalog created "c2003.".
• catalog date "2003".
• catalog date "c2003.".
• catalog dateCopyrighted "c2003.".
• catalog description "Expert practitioners present a comprehensive approach to vaccine development, production, and assessment that can be adapted successfully to any vaccine. Recent advances in vaccine research include those in the areas of bacterial genomics, antigen-specific T Cell quantification, genetic manipulation of vaccine vectors, the harnessing of natural molecules concerned with the regulation of immune responses, and the burgeoning field of DNA vaccinology. This second edition has been thoroughly revised with new chapters on live viral vaccine vectors, attenuated bacterial vectors, immunomodulators, MHC-peptide tetrameric complexes and the identification of vaccine candidates by genomic analysis. Additionally, chapters from the first edition have been updated to accommodate state-of-the-art methods in molecular vaccinology, making this a valuable and relevant practical manual for all those seeking to produce improved or novel vaccines.".
• catalog description "Includes bibliographical references and index.".
• catalog description "Overview of vaccines / G. Ada -- Temperature-sensitive mutant vaccines / C.R. Pringle -- Live viral vectors: construction of a replication-deficient recombinant adenovirus / A.R. Fooks -- Live viral vectors: vaccinia virus / C. Staib and G. Sutter -- Live viral vectors: Semliki Forest virus / G.B. Karlsson and P. Liljestrom -- Development of attenuated Salmonella strains that express heterologous antigens / F. Bowe ... [et al.] -- Expression and delivery of heterologous antigens using lactic acid bacteria / M.A. Reuter, S. Hanniffy and J.M. Wells -- Synthetic peptides / M.J. Francis -- Genetic detoxification of bacterial toxins / M. Pizza ... [et al.] -- Preparation of polysaccharide-conjugate vaccines / C.C. Peeters ... [et al.] -- Adjuvant formulations for experimental vaccines / D.E. Stewart-Tull -- Incorporation of immunomodulators into plasmid DNA vaccines / L.S. Klavinskis, P. Hobson and A. Woods -- Microencapsulation of vaccine antigens / D.H. Jones -- Lyophilization of vaccines: current trends / G.D. Adams -- Stimulation of mucosal immunity / D.J. Lewis and C.M. Hayward -- Induction and detection of T-cell responses / K.H. Mills -- Construction of MHC class I-peptide tetrameric complexes for analysis of T-cell-mediated immune responses / R.V. Samuel and T. Hanke -- Assessment of functional antibody responses / R. Borrow and P. Balmer -- The use of complete genome sequences in vaccine design / N.J. Saunders and S. Butcher -- Severe Combined Immunodeficient (SCID) Mice in Vaccine Assessment / M.J. Dennis -- Clinical trials / P. Farrington and E. Miller -- Assuring the quality and safety of vaccines: regulatory licensing and batch release / E. Griffiths and I. Knezevic -- DNA vaccination: an update / D.B. Lowrie -- From vaccine research to manufacture: a guide for the researcher / N. Allison and H.S. Tranter.".
• catalog extent "xi, 414 p. :".
• catalog identifier "1588291405 (alk. paper)".
• catalog isPartOf "Methods in molecular medicine ; 87".
• catalog issued "2003".
• catalog issued "c2003.".
• catalog language "eng".
• catalog publisher "Totowa, N.J. : Humana Press,".
• catalog subject "615/.372 21".
• catalog subject "Drug Design.".
• catalog subject "Genetic Techniques.".
• catalog subject "QR189 .V2513 2003".
• catalog subject "QW 525 V116 2003".
• catalog subject "Research Design.".
• catalog subject "Vaccines Laboratory manuals.".
• catalog subject "Vaccines.".
• catalog subject "W1 ME9616JM v.87 2003".
• catalog tableOfContents "Overview of vaccines / G. Ada -- Temperature-sensitive mutant vaccines / C.R. Pringle -- Live viral vectors: construction of a replication-deficient recombinant adenovirus / A.R. Fooks -- Live viral vectors: vaccinia virus / C. Staib and G. Sutter -- Live viral vectors: Semliki Forest virus / G.B. Karlsson and P. Liljestrom -- Development of attenuated Salmonella strains that express heterologous antigens / F. Bowe ... [et al.] -- Expression and delivery of heterologous antigens using lactic acid bacteria / M.A. Reuter, S. Hanniffy and J.M. Wells -- Synthetic peptides / M.J. Francis -- Genetic detoxification of bacterial toxins / M. Pizza ... [et al.] -- Preparation of polysaccharide-conjugate vaccines / C.C. Peeters ... [et al.] -- Adjuvant formulations for experimental vaccines / D.E. Stewart-Tull -- Incorporation of immunomodulators into plasmid DNA vaccines / L.S. Klavinskis, P. Hobson and A. Woods -- Microencapsulation of vaccine antigens / D.H. Jones -- Lyophilization of vaccines: current trends / G.D. Adams -- Stimulation of mucosal immunity / D.J. Lewis and C.M. Hayward -- Induction and detection of T-cell responses / K.H. Mills -- Construction of MHC class I-peptide tetrameric complexes for analysis of T-cell-mediated immune responses / R.V. Samuel and T. Hanke -- Assessment of functional antibody responses / R. Borrow and P. Balmer -- The use of complete genome sequences in vaccine design / N.J. Saunders and S. Butcher -- Severe Combined Immunodeficient (SCID) Mice in Vaccine Assessment / M.J. Dennis -- Clinical trials / P. Farrington and E. Miller -- Assuring the quality and safety of vaccines: regulatory licensing and batch release / E. Griffiths and I. Knezevic -- DNA vaccination: an update / D.B. Lowrie -- From vaccine research to manufacture: a guide for the researcher / N. Allison and H.S. Tranter.".
• catalog title "Vaccine protocols / edited by Andrew Robinson, Michael J. Hudson, and Martin P. Cranage.".
• catalog type "Handbooks, manuals, etc. fast".
• catalog type "text".