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2009015172 contributor B11410840.
2009015172 created "c2009.".
2009015172 date "2009".
2009015172 date "c2009.".
2009015172 dateCopyrighted "c2009.".
2009015172 description "Includes bibliographical references and index.".
2009015172 description "The discovery and development of sunitinib (SU11248) : a multitarget tyrosine kinase inhibitor of tumor growth, survival, and angiogenesis / Connie L. Sun, James G. Christensen, and Gerald McMahon -- Tykerb discovery : a dual EGFR and ERBB2 tyrosine kinase inhibitor / Karen Lackey and G. Stuart Cockerill -- Discovery of pazopanib : a pan vascular endothelial growth factor kinase inhibitor / Philip A. Harris and Jeffrey A. Stafford -- The road to ABT-869 : a multitargeted receptor tyrosine kinase inhibitor / Michael Michaelides and Daniel H. Albert -- Discovery of motesanib / Andrew S. Tasker and Vinod F. Patel -- Discovery of brivanib alaninate : a dual vascular endothelial growth factor and fibroblast growth factor receptor inhibitor / Rajeev S. Bhide and Joseph Fargnoli -- Structure-based design and characterization of axitinib / Robert S. Kania -- The road to PD0325901 and beyond : the MEK inhibitors quest / Judith S. Sebolt-Leopold and Alexander J. Bridges -- Discovery of allosteric MEK inhibitors / Eli Wallace and James F. Blake -- Discovery of MK-0457 (VX-680) / Julian M.C. Golec -- Discovery of PHA-739358 / Daniele Fancelli and Jürgen Moll -- Discovery of AZD1152 : a selective inhibitor of aurora-B kinase with potent antitumor activity / Kevin M. Foote and Andrew A. Mortlock -- Case study of aurora-A inhibitor MLN8054 / Christopher F. Claiborne and Mark G. Manfredi -- Discovery of GSK461364 : a polo-like kinase 1 inhibitor for the treatment of cancer / Kevin W. Kuntz and Kyle A. Emmitte -- Pharmacogenomics of dasatinib (Sprycel) / Fei Huang and Edwin A. Clark -- Practical use of computational chemistry in kinase drug discovery / James M. Veal -- Approaches to kinase homology modeling : successes and consideration for the structural kinome / Victoria A. Feher and J. David Lawson -- Fragment-based drug discovery of kinase inhibitors / Daniel A. Erlanson -- Protein kinase structural biology : methods and strategies for targeted drug discovery / Clifford D. Mol, Kengo Okada, and David J. Hosfield.".
2009015172 extent "xv, 510 p., [16] p. of plates :".
2009015172 identifier "0470278293 (cloth)".
2009015172 identifier "9780470278291 (cloth)".
2009015172 isPartOf "Wiley series in drug discovery and development".
2009015172 isPartOf "Wiley series in drug discovery and development.".
2009015172 issued "2009".
2009015172 issued "c2009.".
2009015172 language "eng".
2009015172 publisher "Hoboken, N.J. : Wiley,".
2009015172 subject "615/.798 22".
2009015172 subject "Antineoplastic Agents therapeutic use.".
2009015172 subject "Antineoplastic agents.".
2009015172 subject "Drug Discovery.".
2009015172 subject "Neoplasms drug therapy.".
2009015172 subject "Protein Kinase Inhibitors pharmacology.".
2009015172 subject "Protein Kinase Inhibitors therapeutic use.".
2009015172 subject "Protein Kinases metabolism.".
2009015172 subject "Protein kinases Inhibitors Therapeutic use.".
2009015172 subject "RM666.E548 K56 2009".
2009015172 tableOfContents "The discovery and development of sunitinib (SU11248) : a multitarget tyrosine kinase inhibitor of tumor growth, survival, and angiogenesis / Connie L. Sun, James G. Christensen, and Gerald McMahon -- Tykerb discovery : a dual EGFR and ERBB2 tyrosine kinase inhibitor / Karen Lackey and G. Stuart Cockerill -- Discovery of pazopanib : a pan vascular endothelial growth factor kinase inhibitor / Philip A. Harris and Jeffrey A. Stafford -- The road to ABT-869 : a multitargeted receptor tyrosine kinase inhibitor / Michael Michaelides and Daniel H. Albert -- Discovery of motesanib / Andrew S. Tasker and Vinod F. Patel -- Discovery of brivanib alaninate : a dual vascular endothelial growth factor and fibroblast growth factor receptor inhibitor / Rajeev S. Bhide and Joseph Fargnoli -- Structure-based design and characterization of axitinib / Robert S. Kania -- The road to PD0325901 and beyond : the MEK inhibitors quest / Judith S. Sebolt-Leopold and Alexander J. Bridges -- Discovery of allosteric MEK inhibitors / Eli Wallace and James F. Blake -- Discovery of MK-0457 (VX-680) / Julian M.C. Golec -- Discovery of PHA-739358 / Daniele Fancelli and Jürgen Moll -- Discovery of AZD1152 : a selective inhibitor of aurora-B kinase with potent antitumor activity / Kevin M. Foote and Andrew A. Mortlock -- Case study of aurora-A inhibitor MLN8054 / Christopher F. Claiborne and Mark G. Manfredi -- Discovery of GSK461364 : a polo-like kinase 1 inhibitor for the treatment of cancer / Kevin W. Kuntz and Kyle A. Emmitte -- Pharmacogenomics of dasatinib (Sprycel) / Fei Huang and Edwin A. Clark -- Practical use of computational chemistry in kinase drug discovery / James M. Veal -- Approaches to kinase homology modeling : successes and consideration for the structural kinome / Victoria A. Feher and J. David Lawson -- Fragment-based drug discovery of kinase inhibitors / Daniel A. Erlanson -- Protein kinase structural biology : methods and strategies for targeted drug discovery / Clifford D. Mol, Kengo Okada, and David J. Hosfield.".
2009015172 title "Kinase inhibitor drugs / edited by Rongshi Li, Jeffrey A. Stafford.".
2009015172 type "text".