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- 2009024446 contributor B11422150.
- 2009024446 created "c2010.".
- 2009024446 date "2010".
- 2009024446 date "c2010.".
- 2009024446 dateCopyrighted "c2010.".
- 2009024446 description "Includes bibliographical references and index.".
- 2009024446 description "Introduction to biopharmaceutical conformational analysis : issues and methods -- Comparability of biotechnological/biological products and biological generics -- Application of native electrophoresis for the study of protein conformation -- Affinity chromatography including hydrophobic interaction chromatography in the study of biopolymer conformation -- Size-exclusion chromatography and bimolecular conformation -- Use of analytical ultracentrifugation to study biomolecular conformation -- Use of differential scanning calorimetry to measure conformational change in proteins and other biomacromolecules -- Light scattering and biomacromolecular conformation -- Use of luminescence to measure conformational change in biopharmaceuticals with emphasis on protein and protein drug products -- Near-infrared spectroscopy and macromolecular conformation -- Use of mid-infrared and Fourier transform infrared spectroscopy to study conformation of biomacromolecules -- Use of Raman spectroscopy to evaluate biopharmaceutical conformation -- The use of UV-VIS spectrophotometry for the characterization of biopharmaceutical products -- Use of optical rotatory dispersion and circular dichroism to study therapeutic biomacromolecule conformation -- Use of nuclear magnetic resonance for the characterization of biotherapeutic products -- Use of chemical probes for the study of protein conformation -- Use of hydrogen exchange in the study of biopharmaceutical conformation -- Use of chemical modification for the conformational analysis of biopharmaceuticals -- Use of immunology to characterize biopharmaceutical conformation -- Use of limited proteolysis to study the conformation of proteins of biotechnological interest -- Other technologies for the characterization of conformational change in biopharmaceuticals -- Development of an experimental approach for the study of the conformation of a biological therapeutic product.".
- 2009024446 extent "xiii, 354 p. :".
- 2009024446 identifier "1439807809 (hardcover : alk. paper)".
- 2009024446 identifier "9781439807804 (hardcover : alk. paper)".
- 2009024446 isPartOf "Protein science series".
- 2009024446 isPartOf "Protein science series.".
- 2009024446 issued "2010".
- 2009024446 issued "c2010.".
- 2009024446 language "eng".
- 2009024446 publisher "Boca Raton : CRC Press,".
- 2009024446 subject "2010 B-007".
- 2009024446 subject "615/.7 22".
- 2009024446 subject "Biopharmaceutics methods.".
- 2009024446 subject "Pharmaceutical biotechnology.".
- 2009024446 subject "Protein Conformation.".
- 2009024446 subject "Protein drugs Conformation.".
- 2009024446 subject "Proteins analysis.".
- 2009024446 subject "QV 38 L962a 2010".
- 2009024446 subject "RS431.P75 L86 2010".
- 2009024446 tableOfContents "Introduction to biopharmaceutical conformational analysis : issues and methods -- Comparability of biotechnological/biological products and biological generics -- Application of native electrophoresis for the study of protein conformation -- Affinity chromatography including hydrophobic interaction chromatography in the study of biopolymer conformation -- Size-exclusion chromatography and bimolecular conformation -- Use of analytical ultracentrifugation to study biomolecular conformation -- Use of differential scanning calorimetry to measure conformational change in proteins and other biomacromolecules -- Light scattering and biomacromolecular conformation -- Use of luminescence to measure conformational change in biopharmaceuticals with emphasis on protein and protein drug products -- Near-infrared spectroscopy and macromolecular conformation -- Use of mid-infrared and Fourier transform infrared spectroscopy to study conformation of biomacromolecules -- Use of Raman spectroscopy to evaluate biopharmaceutical conformation -- The use of UV-VIS spectrophotometry for the characterization of biopharmaceutical products -- Use of optical rotatory dispersion and circular dichroism to study therapeutic biomacromolecule conformation -- Use of nuclear magnetic resonance for the characterization of biotherapeutic products -- Use of chemical probes for the study of protein conformation -- Use of hydrogen exchange in the study of biopharmaceutical conformation -- Use of chemical modification for the conformational analysis of biopharmaceuticals -- Use of immunology to characterize biopharmaceutical conformation -- Use of limited proteolysis to study the conformation of proteins of biotechnological interest -- Other technologies for the characterization of conformational change in biopharmaceuticals -- Development of an experimental approach for the study of the conformation of a biological therapeutic product.".
- 2009024446 title "Approaches to the conformational analysis of biopharmaceuticals / Roger L. Lundblad.".
- 2009024446 type "text".