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- 2009045991 contributor B11448203.
- 2009045991 created "2010.".
- 2009045991 date "2010".
- 2009045991 date "2010.".
- 2009045991 dateCopyrighted "2010.".
- 2009045991 description "Chapter 11 Modeling Kidney and Liver Cytotoxicity -- Kai H. Liao, Yu-Mei Tan, Harvey J. Clewell III, and Melvin E. Andersen -- Section4: Modeling tissue and organism responses -- Chapter 12 Computational Model for Iodide Economy and the HPT Axis in the Adult Rat -- Jeffrey W. Fisher and Eva D. McLanahan -- Chapter 13 Two Stage Clonal Growth Modeling of Cancer -- Rory B. Conolly and Melvin E. Andersen -- Chapter 14 Statistical and Physiological Modeling of the Toxicity of Chemicals in Mixtures -- Hisham A. El-Masri, Michael A. Lyons, and Raymond S.H. Yang -- Chapter 15 (Q)SAR Models of Adverse Responses: Acute Systemic Toxicity -- Mark T.D. Cronin, Yana K. Koleva, and Judith C. Madden -- Section5: Model application and evaluation -- Chapter 16 Modeling Exposures to Chemicals from Multiple Sources and Routes -- Panos G. Georgopoulos, Sastry S. Isukapalli, and Kannan Krishnan -- Chapter 17 Probabilistic Reverse Dosimetry Modeling for Interpreting Biomonitoring Data -- Yu-Mei Tan and Harvey J. Clewell III -- Chapter 18 Quantitative Modeling in Noncancer Risk Assessment -- Q. Jay Zhao, Lynne Haber, Melissa Kohrman., Patricia Nance, and Michael Dourson -- Chapter 19 Application of Physiologically Based Pharmacokinetic Modeling in Risk Assessment -- Harvey J. Clewell III -- Chapter 20 Uncertainty, Variability and Sensitivity Analyses in Simulation Models -- Sastry S. Isukapalli, Martin Spendiff, Panos G. Georgopoulos and Kannan Krishnan -- Chapter 21 Evaluation of Quantitative Models in Toxicology: Progress and challenges -- Kannan Krishnan and Melvin E. Andersen.".
- 2009045991 description "Includes bibliographical references and index.".
- 2009045991 description "Machine generated contents note: Preface -- About the Editors -- About the Book -- List of Contributors -- Section1: Introduction -- Chapter 1 Quantitative modeling in toxicology: An introduction -- Melvin E. Andersen and Kannan Krishnan -- Section2: Physiologically-based toxicokinetic and pharmacokinetic (PBPK) modeling -- Chapter 2 PBPK modeling: a primer -- Kannan Krishnan, George Loizou, Martin Spendiff, John Lipscomb and Melvin E. Andersen -- Chapter 3 Pharmacokinetic modeling with Manganese - An essential element -- Andy Nong, Michael Taylor, Miyoung Yoon, and Melvin E. Andersen -- Chapter 4 Physiologically-based modeling of pharmacokinetic interactions in chemical mixtures -- Sami Haddad, Robert Tardif, Jonathan Boyd, and Kannan Krishnan -- Chapter 5 Physiological Parameters and Databases for PBPK Modeling -- Douglas O. Johns, Elizabeth Oesterling Owens, Chad M. Thompson, Babasaheb Sonawane, Dale Hattis and Kannan Krishnan -- Section3: Modeling toxicant-target interactions -- Chapter 6 Modeling cholinesterase Inhibition -- Charles Timchalk, Paul M. Hinderliter,and Torka S. Poet -- Chapter 7 Modeling of Protein Induction and dose-dependent hepatic sequestration -- Andy Nong and Melvin E. Andersen -- Chapter 8 Bistable Signaling Motifs and Cell Fate Decisions -- Sudin Bhattacharya, Qiang Zhang, and Melvin E. Andersen M.E. -- Chapter 9 Ultrasensitive Response Motifs in Biochemical Networks -- Qiang Zhang, Sudin Bhattacharya, Courtney G. Woods, and Melvin E. Andersen -- Chapter 10 Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks -- Melvin E. Andersen, Qiang Zhang, and Sudin Bhattacharya --".
- 2009045991 extent "p. ;".
- 2009045991 identifier "9780470998090 (cloth)".
- 2009045991 issued "2010".
- 2009045991 issued "2010.".
- 2009045991 language "eng".
- 2009045991 publisher "Chichester, West Sussex ; Hoboken : John Wiley & Sons,".
- 2009045991 subject "615.9001/5118 22".
- 2009045991 subject "Environmental Exposure adverse effects.".
- 2009045991 subject "Hazardous Substances toxicity.".
- 2009045991 subject "Models, Biological.".
- 2009045991 subject "QV 602 Q13 2010".
- 2009045991 subject "RA1199.4.M37 Q36 2010".
- 2009045991 subject "Toxicity Tests methods.".
- 2009045991 subject "Toxicology Mathematical models.".
- 2009045991 subject "Toxicology methods.".
- 2009045991 tableOfContents "Chapter 11 Modeling Kidney and Liver Cytotoxicity -- Kai H. Liao, Yu-Mei Tan, Harvey J. Clewell III, and Melvin E. Andersen -- Section4: Modeling tissue and organism responses -- Chapter 12 Computational Model for Iodide Economy and the HPT Axis in the Adult Rat -- Jeffrey W. Fisher and Eva D. McLanahan -- Chapter 13 Two Stage Clonal Growth Modeling of Cancer -- Rory B. Conolly and Melvin E. Andersen -- Chapter 14 Statistical and Physiological Modeling of the Toxicity of Chemicals in Mixtures -- Hisham A. El-Masri, Michael A. Lyons, and Raymond S.H. Yang -- Chapter 15 (Q)SAR Models of Adverse Responses: Acute Systemic Toxicity -- Mark T.D. Cronin, Yana K. Koleva, and Judith C. Madden -- Section5: Model application and evaluation -- Chapter 16 Modeling Exposures to Chemicals from Multiple Sources and Routes -- Panos G. Georgopoulos, Sastry S. Isukapalli, and Kannan Krishnan -- Chapter 17 Probabilistic Reverse Dosimetry Modeling for Interpreting Biomonitoring Data -- Yu-Mei Tan and Harvey J. Clewell III -- Chapter 18 Quantitative Modeling in Noncancer Risk Assessment -- Q. Jay Zhao, Lynne Haber, Melissa Kohrman., Patricia Nance, and Michael Dourson -- Chapter 19 Application of Physiologically Based Pharmacokinetic Modeling in Risk Assessment -- Harvey J. Clewell III -- Chapter 20 Uncertainty, Variability and Sensitivity Analyses in Simulation Models -- Sastry S. Isukapalli, Martin Spendiff, Panos G. Georgopoulos and Kannan Krishnan -- Chapter 21 Evaluation of Quantitative Models in Toxicology: Progress and challenges -- Kannan Krishnan and Melvin E. Andersen.".
- 2009045991 tableOfContents "Machine generated contents note: Preface -- About the Editors -- About the Book -- List of Contributors -- Section1: Introduction -- Chapter 1 Quantitative modeling in toxicology: An introduction -- Melvin E. Andersen and Kannan Krishnan -- Section2: Physiologically-based toxicokinetic and pharmacokinetic (PBPK) modeling -- Chapter 2 PBPK modeling: a primer -- Kannan Krishnan, George Loizou, Martin Spendiff, John Lipscomb and Melvin E. Andersen -- Chapter 3 Pharmacokinetic modeling with Manganese - An essential element -- Andy Nong, Michael Taylor, Miyoung Yoon, and Melvin E. Andersen -- Chapter 4 Physiologically-based modeling of pharmacokinetic interactions in chemical mixtures -- Sami Haddad, Robert Tardif, Jonathan Boyd, and Kannan Krishnan -- Chapter 5 Physiological Parameters and Databases for PBPK Modeling -- Douglas O. Johns, Elizabeth Oesterling Owens, Chad M. Thompson, Babasaheb Sonawane, Dale Hattis and Kannan Krishnan -- Section3: Modeling toxicant-target interactions -- Chapter 6 Modeling cholinesterase Inhibition -- Charles Timchalk, Paul M. Hinderliter,and Torka S. Poet -- Chapter 7 Modeling of Protein Induction and dose-dependent hepatic sequestration -- Andy Nong and Melvin E. Andersen -- Chapter 8 Bistable Signaling Motifs and Cell Fate Decisions -- Sudin Bhattacharya, Qiang Zhang, and Melvin E. Andersen M.E. -- Chapter 9 Ultrasensitive Response Motifs in Biochemical Networks -- Qiang Zhang, Sudin Bhattacharya, Courtney G. Woods, and Melvin E. Andersen -- Chapter 10 Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks -- Melvin E. Andersen, Qiang Zhang, and Sudin Bhattacharya --".
- 2009045991 title "Quantitative modeling in toxicology / editors, Kannan Krishnan, Melvin E. Andersen.".
- 2009045991 type "text".