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- 2012472873 abstract "Formaldehyde is ubiquitous in indoor and outdoor air, and everyone is exposed to formaldehyde at some concentration daily. Formaldehyde is used to produce a wide array of products, particularly building materials; it is emitted from many sources, including power plants, cars, gas and wood stoves, and cigarettes; it is a natural product in some foods; and it is naturally present in the human body as a metabolic intermediate. Much research has been conducted on the health effects of exposure to formaldehyde, including effects on the upper airway, where formaldehyde is deposited when inhaled, and effects on tissues distant from the site of initial contact. The U.S. Environmental Protection Agency (EPA) released noncancer and cancer assessments of formaldehyde for its Integrated Risk Information System (IRIS) in 1990 and 1991, respectively. The agency began reassessing formaldehyde in 1998 and released a draft IRIS assessment in June 2010. Given the complexity of the issues and the knowledge that the assessment will be used as the basis of regulatory decisions, EPA asked the National Research Council (NRC) to conduct an independent scientific review of the draft IRIS assessment. In this report, the Committee to Review EPA's Draft IRIS Assessment of Formaldehyde first addresses some general issues associated with the draft IRIS assessment. The committee next focuses on questions concerning specific aspects of the draft assessment, including derivation of the reference concentrations and the cancer unit risk estimates for formaldehyde. The committee closes with recommendations for improving the IRIS assessment of formaldehyde and provides some general comments on the IRIS development process-- Source other than Library of Congress.".
- 2012472873 contributor B12636433.
- 2012472873 contributor B12636434.
- 2012472873 created "c2011.".
- 2012472873 date "2011".
- 2012472873 date "c2011.".
- 2012472873 dateCopyrighted "c2011.".
- 2012472873 description "Formaldehyde is ubiquitous in indoor and outdoor air, and everyone is exposed to formaldehyde at some concentration daily. Formaldehyde is used to produce a wide array of products, particularly building materials; it is emitted from many sources, including power plants, cars, gas and wood stoves, and cigarettes; it is a natural product in some foods; and it is naturally present in the human body as a metabolic intermediate. Much research has been conducted on the health effects of exposure to formaldehyde, including effects on the upper airway, where formaldehyde is deposited when inhaled, and effects on tissues distant from the site of initial contact. The U.S. Environmental Protection Agency (EPA) released noncancer and cancer assessments of formaldehyde for its Integrated Risk Information System (IRIS) in 1990 and 1991, respectively. The agency began reassessing formaldehyde in 1998 and released a draft IRIS assessment in June 2010. Given the complexity of the issues and the knowledge that the assessment will be used as the basis of regulatory decisions, EPA asked the National Research Council (NRC) to conduct an independent scientific review of the draft IRIS assessment. In this report, the Committee to Review EPA's Draft IRIS Assessment of Formaldehyde first addresses some general issues associated with the draft IRIS assessment. The committee next focuses on questions concerning specific aspects of the draft assessment, including derivation of the reference concentrations and the cancer unit risk estimates for formaldehyde. The committee closes with recommendations for improving the IRIS assessment of formaldehyde and provides some general comments on the IRIS development process-- Source other than Library of Congress.".
- 2012472873 description "Includes bibliographical references.".
- 2012472873 extent "xiii, 190 p. :".
- 2012472873 hasFormat "Also available in Open Book format via the National Academies Press home page.".
- 2012472873 identifier "030921193X (pbk.)".
- 2012472873 identifier "9780309211932 (pbk.)".
- 2012472873 identifier catalog.php?record_id=13142.
- 2012472873 isFormatOf "Also available in Open Book format via the National Academies Press home page.".
- 2012472873 issued "2011".
- 2012472873 issued "c2011.".
- 2012472873 language "eng".
- 2012472873 publisher "Washington, D.C. : National Academies Press,".
- 2012472873 relation "Also available in Open Book format via the National Academies Press home page.".
- 2012472873 spatial "United States.".
- 2012472873 subject "2011 H-519".
- 2012472873 subject "Environmental Exposure adverse effects United States.".
- 2012472873 subject "Formaldehyde Risk assessment.".
- 2012472873 subject "Formaldehyde Toxicology.".
- 2012472873 subject "Formaldehyde pharmacology United States.".
- 2012472873 subject "Formaldehyde toxicity United States.".
- 2012472873 subject "QV 225".
- 2012472873 subject "Risk Assessment United States.".
- 2012472873 subject "TP248.F6 N387 2011".
- 2012472873 subject "United States. Environmental Protection Agency.".
- 2012472873 title "Review of the Environmental Protection Agency's draft IRIS assessment of formaldehyde / Committee to Review EPA's Draft IRIS Assessment of Formaldehyde, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council of the National Academies.".
- 2012472873 type "text".