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- aggregation classification "A1".
- aggregation creator B327156.
- aggregation creator B327157.
- aggregation creator B327158.
- aggregation creator B327159.
- aggregation creator B327160.
- aggregation creator person.
- aggregation date "2001".
- aggregation format "application/pdf".
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- aggregation isPartOf urn:issn:0161-5505.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Automatic determination of left ventricular ejection fraction from gated blood-pool tomography".
- aggregation abstract "The aim of this study was to develop and validate a new algorithm to automatically compute left ventricular ejection fraction (LVEF) from gated blood-pool tomography (GBPT). The results were compared with those of conventional planar radionuclide angiocardiography (PRNA). Methods: Fifty-three consecutive patients received an injection of 740 MBq Tc-99m-labeled human serum albumin. PRNA and GBPT were performed consecutively in a random sequence. PRNA served as the reference, and GBPT images were processed using a new edge detection algorithm. The algorithm is fast (<45 s), fully automatic, and works in three-dimensional space. The method includes identification of the Valve plane and the septum, The left ventricular cavity at end-diastole is delineated by segmentation using an iterative threshold technique. An optimal threshold is reached when the corresponding isocontour best fits the first derivative of the end-diastolic count distribution in three dimensions. This optimal threshold is then applied to delineate the left Ventricular cavity on the other time bins. The data are corrected for the partial-volume effect. Left ventricular Volumes are determined using a geometry-based method and are used to calculate the ejection fraction. Results: The success rate of the new algorithm was 94%, LVEFs calculated from GBPT agreed well with those calculated from PRNA (r = 0.78; GBPT = 0.94 PRNA + 6.33). The systematic error was 2.8%, and the random error was 8.8%. Excellent inter- and intraobserver reproducibility was found, with average differences of 1.1% +/- 4.6% and 1.1% +/- 5.0%, respectively, between the two measurements. Conclusion: This new algorithm provides a fast, automated, and objective method to calculate LVEF from GBPT.".
- aggregation authorList BK617187.
- aggregation endPage "407".
- aggregation issue "3".
- aggregation startPage "401".
- aggregation volume "42".
- aggregation aggregates 3132571.
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