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- aggregation classification "A1".
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- aggregation date "2013".
- aggregation format "application/pdf".
- aggregation hasFormat 3087212.bibtex.
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- aggregation isPartOf urn:issn:0003-4967.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Microscopic gut inflammation in axial spondyloarthritis: a multiparametric predictive model".
- aggregation abstract "Objective : To assess the rates and explore predictors of microscopic gut inflammation in a cohort of patients with axial and peripheral spondyloarthritis (SpA). Methods : Ileocolonoscopy was performed in 65 patients with axial and peripheral SpA from the Gent Inflammatory Arthritis and spoNdylitis cohorT. Histopathological analysis and scoring were performed by an experienced pathologist. Results : Overall, 46.2% of the patients with SpA showed microscopic gut inflammation. In axial SpA, the following parameters were independently associated with gut involvement: male sex (OR = 8.9, p = 0.035); high disease activity measured by the Bath Ankylosing Spondylitis Disease Activity Index (OR = 2.05, p = 0.032); restricted spinal mobility measured by the Bath Ankylosing Spondylitis Metrology Index (OR = 1.94, p = 0.009); and younger age (OR = 0.85, p = 0.013). No clear association was found for human leucocyte antigen-B27 status, presence of peripheral arthritis, enthesitis, uveitis, psoriasis, intake of non-steroidal anti-inflammatory drugs and family history of SpA. The prevalence of gut inflammation in non-radiographic axial SpA and ankylosing spondylitis was comparable. Conclusions : The prevalence of microscopic gut inflammation in SpA remains unaltered over time. Younger age (shorter symptom duration), progressive disease, male sex and higher disease activity are independently associated with microscopic gut inflammation in axial SpA.".
- aggregation authorList BK770100.
- aggregation endPage "417".
- aggregation issue "3".
- aggregation startPage "414".
- aggregation volume "72".
- aggregation aggregates 3231221.
- aggregation isDescribedBy 3087212.
- aggregation similarTo annrheumdis-2012-202135.
- aggregation similarTo LU-3087212.