Matches in UGent Biblio for { <https://biblio.ugent.be/publication/514114#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2008".
- aggregation hasFormat 514114.bibtex.
- aggregation hasFormat 514114.csv.
- aggregation hasFormat 514114.dc.
- aggregation hasFormat 514114.didl.
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- aggregation isPartOf urn:issn:0168-3659.
- aggregation language "eng".
- aggregation publisher "Elsevier".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "New strategies for nucleic acid delivery to conquer cellular and nuclear membranes".
- aggregation abstract "After administration to the body, nucleic acid containing nanoparticles (NANs) need to cross several extra- and intracellular barriers to reach the cytoplasm or nucleus of the target cells. In the last decade several groups tried to overcome these barriers by arming non-viral delivery systems with targeting moieties, polyethylene glycol chains, fusogenic peptides and so forth. However, the drawback of this upgrading strategy is that each of the encountered barriers requires a new functionality, leading to very complex multicomponent NANs. Moreover, there are currently no components available that can efficiently transport genes or NANs inside the nucleus of non-dividing cells. In this article a new, ultrasound based delivery system that possesses the capacity to simultaneously overcome several key barriers in non-viral nucleic acid delivery is presented. Additionally, a small amphiphilic compound that induces nuclear uptake of plasmid DNA and enhances non-viral gene transfer is presented.".
- aggregation authorList BK684844.
- aggregation endPage "288".
- aggregation issue "3".
- aggregation startPage "279".
- aggregation volume "132".
- aggregation isDescribedBy 514114.
- aggregation similarTo j.jconrel.2008.06.023.
- aggregation similarTo LU-514114.